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下颌下神经鞘瘤的临床研究。

A clinical study of submandibular schwannoma.

作者信息

Park Keon Woo, Lee Dong Hoon, Lee Joon Kyoo, Lim Sang Chul

机构信息

Department of Otolaryngology-Head and Neck Surgery, Chonnam National University Medical School & Hwasun Hospital, Hwasun, South Korea.

Department of Otolaryngology-Head and Neck Surgery, Chonnam National University Medical School & Hwasun Hospital, Hwasun, South Korea.

出版信息

Oral Surg Oral Med Oral Pathol Oral Radiol. 2022 Jan;133(1):e6-e9. doi: 10.1016/j.oooo.2021.07.005. Epub 2021 Jul 16.

Abstract

OBJECTIVE

Schwannoma is a slowly growing benign neurogenic tumor that develops from the cells of the nerve sheath. The occurrence of schwannoma in the submandibular space is very rare.

MATERIALS AND METHODS

From January 2010 to March 2021, we reviewed all patients who had been operated on in the otolaryngology department over 11 years and found 61 patients diagnosed with schwannomas at the final biopsy after surgery. In these patients, only 3 submandibular schwannomas were identified, and their clinical characteristics were analyzed.

RESULTS

Three schwannomas (4.9%) developed in the submandibular space. The main symptoms were neck swelling followed by neck discomfort. All submandibular schwannomas were removed surgically with a transcervical approach under general anesthesia. Two patients, who were diagnosed preoperative submandibular tumors, were considered to have developed schwannomas from the lingual nerve, and 1 patient was considered to have developed a schwannoma from the hypoglossal nerve. There were no major surgical complications, including postoperative nerve damage.

CONCLUSIONS

Submandibular schwannomas are extremely rare, but they should be included in the differential diagnosis of submandibular tumors.

摘要

目的

施万细胞瘤是一种生长缓慢的良性神经源性肿瘤,由神经鞘细胞发展而来。发生于下颌下间隙的施万细胞瘤极为罕见。

材料与方法

回顾2010年1月至2021年3月期间在耳鼻喉科接受手术治疗超过11年的所有患者,发现61例患者术后最终活检诊断为施万细胞瘤。在这些患者中,仅发现3例下颌下施万细胞瘤,并对其临床特征进行分析。

结果

3例(4.9%)施万细胞瘤发生于下颌下间隙。主要症状为颈部肿胀,其次为颈部不适。所有下颌下施万细胞瘤均在全身麻醉下经颈部入路手术切除。2例术前诊断为下颌下肿瘤的患者,被认为是由舌神经发生的施万细胞瘤,1例患者被认为是由舌下神经发生的施万细胞瘤。未发生包括术后神经损伤在内的重大手术并发症。

结论

下颌下施万细胞瘤极为罕见,但在诊断下颌下肿瘤时应将其纳入鉴别诊断。

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