Department of Otorhinolaryngology - Head and Neck Surgery, Hospital Queen Elizabeth, Kota Kinabalu, Malaysia.
Department of Otorhinolaryngology, Head and Neck Surgery, Faculty of Medicine, Universiti Kebangsaan Malaysia, Bangi, Selangor, Malaysia.
BMJ Case Rep. 2023 Aug 27;16(8):e253868. doi: 10.1136/bcr-2022-253868.
SummarySchwannoma, a type of benign neurological tumour arising from Schwann cells, is commonly seen in the head and neck region. However, the incidence of cervical lymph node schwannoma is extremely rare, with only two cases reported in the literature. Schwannomatosis is a disease characterised by a constellation of multiple schwannomas seen in a patient, guided by at least one confirmational histological diagnosis. This is a case of a painless progressively enlarging submandibular swelling which is confirmed as a schwannoma based on histology. The patient is also diagnosed with schwannomatosis as the patient has multiple neurological tumours. Nodal schwannoma has a good prognosis and no documentation of recurrence in the literature. It may arise from sympathetic nerves located within the lymph node.
神经鞘瘤是一种起源于施万细胞的良性神经肿瘤,常见于头颈部。然而,发生于颈部淋巴结的神经鞘瘤极其罕见,文献中仅报告过两例。神经鞘瘤病是一种以至少一次组织学确认诊断为指导,在患者身上出现多个神经鞘瘤为特征的疾病。这是一例无疼痛、逐渐增大的下颌下肿胀,根据组织学检查被确诊为神经鞘瘤。该患者还被诊断为神经鞘瘤病,因为患者有多个神经肿瘤。淋巴结神经鞘瘤预后良好,文献中无复发的记录。它可能起源于位于淋巴结内的交感神经。