Department of Chemistry, St. Thomas College Pala, Arunapuram P.O., Kottayam, Kerala, 686574, India.
Department of Chemistry, Alphonsa College Pala, Arunapuram P.O., Kottayam, Kerala, 686574, India.
Org Biomol Chem. 2021 Sep 29;19(37):7995-8008. doi: 10.1039/d1ob01352a.
The chroman-4-one framework is a significant structural entity that belongs to the class of oxygen-containing heterocycles. It acts as a major building block in a large class of medicinal compounds, and synthetic compounds exhibit a broad variety of remarkable biological and pharmaceutical activities. Several studies have been performed to improve the methodologies of 4-chromanone-derived compounds. This review focuses on the major synthetic methods of preparation reported on chroman-4-one derivatives from 2016 to 2021.
色满酮骨架是一种重要的结构单元，属于含氧杂环化合物。它是一大类药用化合物的主要构建模块，合成化合物表现出广泛的显著的生物和药物活性。已经进行了一些研究来改进 4-色满酮衍生化合物的方法。本综述重点介绍了 2016 年至 2021 年报道的色满-4-酮衍生物的主要合成方法。
