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乳腺癌筛查中当日诊断成像的差异:在 COVID-19 大流行期间实施即时读筛查乳房 X 光摄影计划的影响。

Disparities in Same-Day Diagnostic Imaging in Breast Cancer Screening: Impact of an Immediate-Read Screening Mammography Program Implemented During the COVID-19 Pandemic.

机构信息

Department of Radiology, Massachusetts General Hospital, 55 Fruit St, WAC-240, Boston, MA 02114.

Department of Radiology, Harvard Medical School, Boston, MA.

出版信息

AJR Am J Roentgenol. 2022 Feb;218(2):270-278. doi: 10.2214/AJR.21.26597. Epub 2021 Sep 8.

DOI:10.2214/AJR.21.26597
PMID:34494449
Abstract

The need for second visits between screening mammography and diagnostic imaging contributes to disparities in the time to breast cancer diagnosis. During the COVID-19 pandemic, an immediate-read screening mammography program was implemented to reduce patient visits and decrease time to diagnostic imaging. The purpose of this study was to measure the impact of an immediate-read screening program with focus on disparities in same-day diagnostic imaging after abnormal findings are made at screening mammography. In May 2020, an immediate-read screening program was implemented whereby a dedicated breast imaging radiologist interpreted all screening mammograms in real time; patients received results before discharge; and efforts were made to perform any recommended diagnostic imaging during the visit (performed by different radiologists). Screening mammographic examinations performed from June 1, 2019, through October 31, 2019 (preimplementation period), and from June 1, 2020, through October 31, 2020 (postimplementation period), were retrospectively identified. Patient characteristics were recorded from the electronic medical record. Multivariable logistic regression models incorporating patient age, race and ethnicity, language, and insurance type were estimated to identify factors associated with same-day diagnostic imaging. Screening metrics were compared between periods. A total of 8222 preimplementation and 7235 postimplementation screening examinations were included; 521 patients had abnormal screening findings before implementation, and 359 after implementation. Before implementation, 14.8% of patients underwent same-day diagnostic imaging after abnormal screening mammograms. This percentage increased to 60.7% after implementation. Before implementation, patients who identified their race as other than White had significantly lower odds than patients who identified their race as White of undergoing same-day diagnostic imaging after receiving abnormal screening results (adjusted odds ratio, 0.30; 95% CI, 0.10-0.86; = .03). After implementation, the odds of same-day diagnostic imaging were not significantly different between patients of other races and White patients (adjusted odds ratio, 0.92; 95% CI, 0.50-1.71; = .80). After implementation, there was no significant difference in race and ethnicity between patients who underwent and those who did not undergo same-day diagnostic imaging after receiving abnormal results of screening mammography ( > .05). The rate of abnormal interpretation was significantly lower after than it was before implementation (5.0% vs 6.3%; < .001). Cancer detection rate and PPV1 (PPV based on positive findings at screening examination) were not significantly different before and after implementation ( > .05). Implementation of the immediate-read screening mammography program reduced prior racial and ethnic disparities in same-day diagnostic imaging after abnormal screening mammograms. An immediate-read screening program provides a new paradigm for improved screening mammography workflow that allows more rapid diagnostic workup with reduced disparities in care.

摘要

在筛查性乳房 X 光检查和诊断性影像学之间进行二次就诊的需求导致了乳腺癌诊断时间的差异。在 COVID-19 大流行期间,实施了即时读取筛查计划,以减少患者就诊次数并缩短诊断影像学检查的时间。本研究的目的是测量即时读取筛查计划的影响,重点是在筛查性乳房 X 光检查发现异常后,当日进行诊断影像学检查的差异。 2020 年 5 月,实施了即时读取筛查计划,专门的乳房成像放射科医生实时解读所有筛查性乳房 X 光片;患者在出院前获得结果;并努力在就诊期间进行任何推荐的诊断影像学检查(由不同的放射科医生进行)。回顾性确定了 2019 年 6 月 1 日至 2019 年 10 月 31 日(实施前)和 2020 年 6 月 1 日至 2020 年 10 月 31 日(实施后)期间进行的筛查性乳房 X 光检查。从电子病历中记录患者特征。采用包含患者年龄、种族和民族、语言和保险类型的多变量逻辑回归模型,确定与当日进行诊断影像学检查相关的因素。比较了两个时期的筛查指标。共纳入 8222 例实施前和 7235 例实施后筛查检查;521 例患者在实施前有异常筛查发现,359 例在实施后有异常筛查发现。在实施前,有 14.8%的异常筛查性乳房 X 光检查患者进行了当日的诊断影像学检查。实施后,这一比例增加到 60.7%。在实施前,与白人患者相比,将自己的种族认定为其他种族的患者接受异常筛查结果后接受当日诊断影像学检查的可能性显著降低(调整后的优势比,0.30;95%置信区间,0.10-0.86;=.03)。实施后,其他种族患者与白人患者当日进行诊断影像学检查的可能性无显著差异(调整后的优势比,0.92;95%置信区间,0.50-1.71;=.80)。实施后,接受异常筛查结果后当日进行诊断影像学检查和未进行当日诊断影像学检查的患者之间的种族和民族无显著差异( >.05)。实施后异常解读率明显低于实施前(5.0%比 6.3%;<.001)。癌症检出率和 PPV1(基于筛查检查阳性结果的 PPV)在实施前后无显著差异( >.05)。 即时读取筛查性乳房 X 光检查计划的实施减少了异常筛查性乳房 X 光检查后当日诊断影像学检查的先前种族和民族差异。即时读取筛查计划为改善筛查性乳房 X 光检查工作流程提供了一个新的范例,允许更快速的诊断检查,并减少了护理中的差异。

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