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Cytochrome P450-mediated hydroxylation is required for polyketide macrolactonization in stambomycin biosynthesis.
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Identification of a bioactive 51-membered macrolide complex by activation of a silent polyketide synthase in Streptomyces ambofaciens.
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Mukaiyama aldol reaction: an effective asymmetric approach to access chiral natural products and their derivatives/analogues.
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Engineering the stambomycin modular polyketide synthase yields 37-membered mini-stambomycins.
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2
Total synthesis: the structural confirmation of natural products.
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NMR Calculations with Quantum Methods: Development of New Tools for Structural Elucidation and Beyond.
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The optimal DFT approach in DP4 NMR structure analysis - pushing the limits of relative configuration elucidation.
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Total Synthesis of Putative Chagosensine.
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