Yu Zhang, Ling Liu
Department of Neurology, West China Hospital, Sichuan University, Wai Nan Guo Xue Lane 37 #, 610041, Chengdu, Sichuan, China.
Department of Neurology, Chengdu Shangjin Nanfu Hospital, Shang Jin Road 253#, 610000, Chengdu, Sichuan, China.
BMC Neurol. 2021 Sep 8;21(1):344. doi: 10.1186/s12883-021-02373-8.
This study aimed to investigate the association between nutritional characteristics in patients with refractory convulsive status epilepticus.
We retrospectively enrolled 73 patients with refractory convulsive status epilepticus over 18 years of age at the West China Hospital between January 2017 and May 2019. All patients met the 2016 International League Against Epilepsy diagnostic criteria for refractory convulsive status epilepticus. A logistic regression model was used to evaluate the association between malnutrition and refractory convulsive status epilepticus.
Of the 73 patients with refractory convulsive status epilepticus, 33 (45.21 %) suffered from malnutrition during hospitalization, and duration of hospitalization in days (OR = 1.251; 95 % CI,-1.067-1.384; P = 0.007), nasal feeding (OR = 22.623; 95 % CI: 1.091-286.899; P = 0.013), and malnutrition on admission (OR = 30.760; 95 % CI: 1.064-89.797; P = 0.046) were significantly associated with malnutrition in patients with refractory convulsive status epilepticus.
Malnutrition is a common complication during hospitalization in patients with refractory convulsive status epilepticus. The duration of hospitalization (days), nasal feeding, and malnutrition at admission are associated with malnutrition in patients with refractory convulsive status epilepticus. Further longitudinal studies are needed to identify the relationship between refractory convulsive status epilepticus and adverse outcomes.
本研究旨在调查难治性惊厥性癫痫持续状态患者的营养特征之间的关联。
我们回顾性纳入了2017年1月至2019年5月期间在华西医院就诊的73例年龄超过18岁的难治性惊厥性癫痫持续状态患者。所有患者均符合2016年国际抗癫痫联盟难治性惊厥性癫痫持续状态的诊断标准。采用逻辑回归模型评估营养不良与难治性惊厥性癫痫持续状态之间的关联。
在73例难治性惊厥性癫痫持续状态患者中，33例（45.21%）在住院期间出现营养不良，住院天数（OR = 1.251；95% CI：-1.067 - 1.384；P = 0.007）、鼻饲（OR = 22.623；95% CI：1.091 - 286.899；P = 0.013）以及入院时的营养不良（OR = 30.760；95% CI：1.064 - 89.797；P = 0.046）与难治性惊厥性癫痫持续状态患者的营养不良显著相关。
营养不良是难治性惊厥性癫痫持续状态患者住院期间常见的并发症。住院天数、鼻饲以及入院时的营养不良与难治性惊厥性癫痫持续状态患者的营养不良有关。需要进一步的纵向研究来确定难治性惊厥性癫痫持续状态与不良结局之间的关系。
