肝脏灌注指数检测肝转移灶的可靠性。

Reliability of the hepatic perfusion index for the detection of liver metastases.

作者信息

Perkins A C, Whalley D R, Ballantyne K C, Hardcastle J D

机构信息

Department of Medical Physics, University Hospital Queen's Medical Centre, Nottingham, UK.

出版信息

Nucl Med Commun. 1987 Dec;8(12):982-9. doi: 10.1097/00006231-198712000-00006.

DOI:10.1097/00006231-198712000-00006

PMID:3449794

Abstract

The reliability of the technique for measuring the hepatic perfusion index (HPI) for the detection of liver metastases has been examined. Dynamic images from 173 patients with primary and recurrent colorectal cancer have been analysed by two operators using the peak values of both the right and left kidney time-activity curves. In 14.4% of analyses the right kidney HPI method failed, while only 5.7% of analyses failed using the left kidney method. The results showed (a) that disagreement between the operators HPI values was small but statistically significant (p less than 0.05) and (b) that disagreement between the two methods was highly significant (p less than 10(-7)), with the left kidney method resulting in a lower HPI value. An upper limit of normal for left kidney HPI of 0.37 was predicted from the data, assuming the corresponding right kidney value to be 0.40.

摘要

对用于检测肝转移的肝灌注指数（HPI）测量技术的可靠性进行了研究。两名操作人员使用左右肾时间-活性曲线的峰值，对173例原发性和复发性结直肠癌患者的动态图像进行了分析。在14.4%的分析中，右肾HPI方法失败，而使用左肾方法时只有5.7%的分析失败。结果表明：（a）操作人员之间的HPI值差异较小，但具有统计学意义（p<0.05）；（b）两种方法之间的差异高度显著（p<10⁻⁷），左肾方法得出的HPI值较低。根据数据预测，假设相应的右肾值为0.40，则左肾HPI的正常上限为0.37。