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一例睾丸网腺癌对基于顺铂的化疗产生持久反应。

A case of adenocarcinoma of the rete testis with durable response to cisplatin-based chemotherapy.

作者信息

Owa Shunsuke, Sasaki Takeshi, Uchida Katsunori, Watanabe Susumu, Kato Momoko, Sugino Yusuke, Kato Manabu, Masui Satoru, Nishikawa Kouhei, Yoshio Yuko, Kanda Hideki, Sugimura Yoshiki, Inoue Takahiro

机构信息

Department of Nephro-Urologic Surgery and Andrology Mie University Hospital Tsu Mie Japan.

Department of Pathology Mie University Hospital Tsu Mie Japan.

出版信息

IJU Case Rep. 2021 Jun 19;4(5):267-271. doi: 10.1002/iju5.12298. eCollection 2021 Sep.

DOI:10.1002/iju5.12298
PMID:34497979
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8413206/
Abstract

INTRODUCTION

Adenocarcinoma of the rete testis is a rare malignancy with a poor prognosis. We report a case of adenocarcinoma of the rete testis with a durable response to cisplatin-based chemotherapy.

CASE PRESENTATION

A 48-year-old man with Down syndrome (trisomy 21) presented with a 1-month history of painless swelling of the left scrotum. The physical examination revealed a left testis with a hydrocele associated with a tumor and enlarged pelvic and para-aortic lymph nodes. He underwent a radical orchiectomy. The specimen was diagnosed as adenocarcinoma of the rete testis. The patient received 7 cycles of chemotherapy (1 cycle of BEP and 6 cycles of EP) postoperatively. The metastatic lymph nodes were reduced in size for at least 12 months. Our patient with adenocarcinoma of the rete testis obtained an acceptable response to cisplatin-based chemotherapy.

CONCLUSION

We treated a patient with an adenocarcinoma of the rete testis who had an acceptable response to platinum-based chemotherapy.

摘要

引言

睾丸网腺癌是一种罕见的恶性肿瘤,预后较差。我们报告一例睾丸网腺癌患者,对基于顺铂的化疗有持久反应。

病例介绍

一名48岁的唐氏综合征(21三体)男性患者,有1个月左侧阴囊无痛性肿胀病史。体格检查发现左侧睾丸伴有鞘膜积液及肿瘤,盆腔和腹主动脉旁淋巴结肿大。他接受了根治性睾丸切除术。标本诊断为睾丸网腺癌。患者术后接受了7个周期的化疗(1个周期的BEP方案和6个周期的EP方案)。转移淋巴结大小缩小至少12个月。我们的睾丸网腺癌患者对基于顺铂的化疗获得了可接受的反应。

结论

我们治疗了一名睾丸网腺癌患者,其对铂类化疗有可接受的反应。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0636/8413206/c36532273288/IJU5-4-267-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0636/8413206/d97d9a5ec2fb/IJU5-4-267-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0636/8413206/6765ade6d99f/IJU5-4-267-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0636/8413206/a9bf49c483a7/IJU5-4-267-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0636/8413206/c36532273288/IJU5-4-267-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0636/8413206/d97d9a5ec2fb/IJU5-4-267-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0636/8413206/6765ade6d99f/IJU5-4-267-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0636/8413206/a9bf49c483a7/IJU5-4-267-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0636/8413206/c36532273288/IJU5-4-267-g001.jpg

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Adenocarcinoma of the Rete Testis: Clinicopathologic and Immunohistochemical Characterization of 6 Cases and Review of the Literature.睾丸网腺癌:6 例临床病理和免疫组织化学特征及文献复习。
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Editorial Comment to A case of adenocarcinoma of the rete testis with durable response to cisplatin-based chemotherapy.对一例睾丸网腺癌对铂类化疗有持久反应的病例的编辑评论
IJU Case Rep. 2021 Jun 21;4(5):271-272. doi: 10.1002/iju5.12326. eCollection 2021 Sep.
睾丸网腺癌的积极手术治疗
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