Chakraborty T K, Filshie R J, Lee M R
Department of Medicine, Royal Infirmary of Edinburgh.
Scott Med J. 1987 Dec;32(6):185-6. doi: 10.1177/003693308703200610.
Life threatening methaemoglobinaemia developed after prolonged therapeutic use of phenazopyridine (Pyridium) in a patient with chronic obstructive airways disease. The combination of chronic obstructive airways disease and oxidant drugs (methaemoglobinaemia) may be lethal. The use of phenazopyridine should be abandoned. Certainly there is no indication to use it for more than a few days in any patient.
一名患有慢性阻塞性气道疾病的患者在长期使用非那吡啶(吡啶鎓)进行治疗后,出现了危及生命的高铁血红蛋白血症。慢性阻塞性气道疾病与氧化药物(高铁血红蛋白血症)的联合使用可能是致命的。应停止使用非那吡啶。当然,在任何患者中都没有理由使用它超过几天。