Murray P R, Van Scoy R E, Roberts G D
Mayo Clin Proc. 1977 Jan;52(1):42-5.
Four hundred forty samples of sputa and bronchial washings were examined microscopically for evidence of pulmonary and oropharyngeal secretions. Most (88%) sputa showed definite evidence of oropharyngeal contamination, whereas bronchial washings showed much less frequent (21%) contamination. Culture results of the same specimens showed that yeasts (excluding dimorphic fungi) were recovered from 74% of the sputa and 25% of the bronchial washings. It seems that microscopic evidence of oropharyngeal contamination is a reliable index for predicting the presence of yeasts in respiratory secretions. Their presence in cultures of respiratory secretions probably represents "normal flora" except for Cryptococcus neoformans, and their routine identification is not warranted.
对440份痰液和支气管灌洗样本进行显微镜检查，以寻找肺部和口咽分泌物的证据。大多数（88%）痰液显示有口咽污染的确切证据，而支气管灌洗样本的污染频率则低得多（21%）。相同样本的培养结果显示，酵母菌（不包括双相真菌）在74%的痰液和25%的支气管灌洗样本中被检出。口咽污染的显微镜证据似乎是预测呼吸道分泌物中酵母菌存在的可靠指标。除新型隐球菌外，它们在呼吸道分泌物培养物中的存在可能代表“正常菌群”，因此无需对其进行常规鉴定。
