Department of Histopathology, Army Medical College, Rawalpindi, Pakistan.
J Coll Physicians Surg Pak. 2021 Sep;31(9):1108-1110. doi: 10.29271/jcpsp.2021.09.1108.
High-grade serous carcinoma (HGSC) of ovary is the commonest of all ovarian malignant tumours and is associated with high mortality rate. Serous tubal intraepithelial carcinoma (STIC) is believed to be the precursor lesion. In literature, only 40-50% of HGSC shows concurrent STIC, even after thorough sampling. We, herein, present a case of a 40-year female, who underwent staging laparotomy for bilateral ovarian carcinoma. She was diagnosed as HGSC of both ovaries. Left ovary capsule was focally ruptured. Peritoneal washings showed metastatic carcinoma. Provisional FIGO stage was IC. During sampling, concurrent finding of STIC was documented in right fallopian tube. No invasive carcinoma was present in both entirely submitted fallopian tubes. Key Words: High grade serous carcinoma, Ovary, Serous tubal intraepithelial carcinoma, TP53.
卵巢高级别浆液性癌（HGSC）是最常见的卵巢恶性肿瘤，死亡率高。浆液性输卵管上皮内癌（STIC）被认为是其前体病变。文献报道，即使进行彻底取样，HGSC 中也只有 40%-50% 同时存在 STIC。我们在此报告一例 40 岁女性，因双侧卵巢癌行分期剖腹术。她被诊断为双侧卵巢 HGSC。左卵巢包膜局灶性破裂。腹腔冲洗液显示转移性癌。暂定 FIGO 分期为 IC 期。在取样过程中，在右侧输卵管中发现了同时存在的 STIC。在完全送检的两条输卵管中均未发现浸润性癌。关键词：高级别浆液性癌、卵巢、浆液性输卵管上皮内癌、TP53。
