Fischer Laura, Maurins Uldis, Rabe Eberhard, Rits Juris, Kadiss Arnolds, Prave Sandra, Vigants Rets, Pannier Felizitas
Department of Dermatology, University of Essen, Esmarchstraße 14, 45147 Essen, Germany.
Vein Clinic, LV-1000 Riga, Latvia.
J Clin Med. 2021 Aug 27;10(17):3861. doi: 10.3390/jcm10173861.
The aim of this study was to demonstrate the effects of compression following the endovenous laser ablation (EVLA) of incompetent great saphenous veins (GSVs) using a 1470 nm diode laser (Ceralas E 1470 nm, biolitec) and a 2ring radial fiber (ELVeS Radial 2ring™, biolitec). In this single-center prospective study, 150 legs of 150 consecutive patients were randomly allocated to one of three groups (A, B, and C). Group A patients did not undergo postoperative compression. Group B patients wore a thigh-length graduated compression stocking (23-32 mmHg) for 7 days, whereas group C patients wore the same stocking for 28 days. No additional phlebectomies or sclerotherapies were performed. Investigations were performed prior to intervention, at the day of intervention (D0), at day 7 (D7), and at day 28 post intervention (D28). The primary endpoint was post-interventional pain measured on a 10-point scale. A significant but small pain decrease was observed in the first week of compression, by comparing group B's mean pain scores to those of group A ( = 0.009). Wearing a compression stocking after EVLA reduced pain within the first week on a significant, but low level. Taking the very low differences in pain levels into account, the difference may not be clinically relevant and post-treatment compression may not be necessary if no additional phlebectomies or sclerotherapies are performed.
本研究的目的是证明使用1470纳米二极管激光（Ceralas E 1470 nm，伯乐泰克）和2环径向光纤（ELVeS Radial 2ring™，伯乐泰克）对大隐静脉功能不全进行腔内激光消融（EVLA）后压迫的效果。在这项单中心前瞻性研究中，150例连续患者的150条腿被随机分为三组（A组、B组和C组）。A组患者术后未进行压迫。B组患者穿着大腿长度的分级压力弹力袜（23 - 32 mmHg）7天，而C组患者穿着相同的弹力袜28天。未进行额外的静脉切除术或硬化疗法。在干预前、干预当天（D0）、第7天（D7）和干预后第28天（D28）进行调查。主要终点是用10分制测量的干预后疼痛。通过比较B组和A组的平均疼痛评分，在压迫的第一周观察到疼痛有显著但较小的降低（P = 0.009）。腔内激光消融术后穿着压力弹力袜在第一周内可显著减轻疼痛，但程度较低。考虑到疼痛水平的差异非常小，这种差异可能在临床上不相关，如果未进行额外的静脉切除术或硬化疗法，治疗后可能无需压迫。
