Giorgianni Andrea, Molinaro Stefano, Agosti Edoardo, Terrana Alberto Vito, Vizzari Francesco Alberto, Arosio Alberto Daniele, Pietrobon Giacomo, Volpi Luca, Turri-Zanoni Mario, Craparo Giuseppe, Piacentino Filippo, Castelnuovo Paolo, Baruzzi Fabio Massimo, Bignami Maurizio
Neuroradiology Unit, ASST Sette Laghi-Circolo Hospital, 21100 Varese, Italy.
Department of Biotechnology and Life Sciences, Division of Neurosurgery, University of Insubria, 21100 Varese, Italy.
J Clin Med. 2021 Aug 31;10(17):3926. doi: 10.3390/jcm10173926.
Juvenile nasopharyngeal angiofibroma (JNA) is a benign tumor of the nasal cavity that predominantly affects young boys. Surgical removal remains the gold standard for the management of this disease. Preoperative intra-arterial embolization (PIAE) is useful for reductions in intraoperative blood loss and surgical complications. In our series of 79 patients who underwent preoperative embolization from 1999 to 2020, demographics, procedural aspects, surgical management and follow-up outcome were analyzed. Embolization was performed in a similar fashion for all patients, with a superselective microcatheterization of external carotid artery (ECA) feeders and an injection of polyvinyl alcohol (PVA) particles, followed, in some cases, by the deployment of coils . Procedural success was reached in 100% of cases, with no complications such as bleeding or thromboembolic occlusion, and surgical intraoperative blood loss was significantly decreased. In conclusion, PIAE is a safe and effective technique in JNA treatment, minimizing intraoperative bleeding.
青少年鼻咽血管纤维瘤（JNA）是一种主要影响年轻男性的鼻腔良性肿瘤。手术切除仍然是该疾病治疗的金标准。术前动脉内栓塞（PIAE）有助于减少术中失血和手术并发症。在我们1999年至2020年期间接受术前栓塞的79例患者系列中，分析了人口统计学、手术过程、手术管理和随访结果。所有患者均以类似方式进行栓塞，对颈外动脉（ECA）供血支进行超选择性微导管插入并注射聚乙烯醇（PVA）颗粒，在某些情况下随后放置弹簧圈。100%的病例手术成功，无出血或血栓栓塞性闭塞等并发症，手术术中失血量显著减少。总之，PIAE是JNA治疗中一种安全有效的技术，可最大限度减少术中出血。
