Lewis Yael Doreen, Kapon Shirley, Enoch-Levy Adi, Yaroslavsky Amit, Witztum Eliezer, Stein Daniel
Hadarim Eating Disorders Center, Shalvata Mental Health Center, Hod Hasharon 4534708, Israel.
Department of Psychiatry, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.
J Clin Med. 2021 Sep 6;10(17):4027. doi: 10.3390/jcm10174027.
In patients with eating disorders (EDs), elevated dissociation may increase the risk of suicide. Bodily related disturbances, depression, and anxiety may intervene in the association between dissociation and suicidality. In this study we aimed to examine the influence of bodily related disturbances, depression, anxiety, severity of ED symptoms, body mass index (BMI), and type and duration of the ED on the relationship between elevated dissociation and elevated suicidality. The study included 172 inpatients: 65 with anorexia nervosa restricting type, 60 with anorexia nervosa binge/purge type, and 37 with bulimia nervosa. Participants were assessed using self-rating questionnaires for dissociation, suicidality, bodily related parameters, and severity of ED symptomatology, depression, and anxiety. We found that dissociation and suicidality were directly associated. In addition, depression and anxiety moderated the mediating role of body image parameters in the association between increased dissociation and increased suicidality. Thus, only in inpatients with high depression and anxiety, i.e., above the median range, body image disturbances were found to mediate the association between dissociation and suicidality. ED-related parameters did not moderate these relationships. Our study demonstrates that in inpatients with EDs, increased dissociation may be significantly associated with increased suicidality, both directly and via the intervening influence of body image, depression, and anxiety.
在饮食失调(EDs)患者中,解离程度升高可能会增加自杀风险。与身体相关的障碍、抑郁和焦虑可能会干预解离与自杀倾向之间的关联。在本研究中,我们旨在探讨与身体相关的障碍、抑郁、焦虑、饮食失调症状的严重程度、体重指数(BMI)以及饮食失调的类型和持续时间对解离程度升高与自杀倾向升高之间关系的影响。该研究纳入了172名住院患者:65名患有节食型神经性厌食症,60名患有暴食/清除型神经性厌食症,37名患有神经性贪食症。使用自评问卷对参与者进行解离、自杀倾向、与身体相关的参数以及饮食失调症状学、抑郁和焦虑的严重程度评估。我们发现解离与自杀倾向直接相关。此外,抑郁和焦虑调节了身体意象参数在解离增加与自杀倾向增加之间关联中的中介作用。因此,仅在抑郁和焦虑程度较高(即高于中位数范围)的住院患者中,发现身体意象障碍介导了解离与自杀倾向之间的关联。与饮食失调相关的参数并未调节这些关系。我们的研究表明,在饮食失调的住院患者中,解离增加可能与自杀倾向增加显著相关,这既直接相关,也通过身体意象、抑郁和焦虑的干预影响相关。