Department of Pathology, Molecular and Cell-based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Mod Pathol. 2022 Jan;35(Suppl 1):1-7. doi: 10.1038/s41379-021-00915-6. Epub 2021 Sep 9.
Recent world events have refocused attention on the pathology associated with clinical acute respiratory distress syndrome (ARDS). The vast majority of cases of clinical ARDS will have diffuse alveolar damage (DAD) histologically, but other histologies may occur less frequently. The aim of this paper is to provide a review of the pathology of DAD and acute fibrinous and organizing pneumonia and provide insights into the pathologic features associated with the E-cigarette/vaping-associated lung-injury outbreak and the ongoing SARS-CoV-2 pandemic.
近期的世界事件使人们重新关注与临床急性呼吸窘迫综合征（ARDS）相关的病理学。临床上绝大多数 ARDS 病例的组织学表现为弥漫性肺泡损伤（DAD），但其他组织学表现则较少见。本文旨在对 DAD 和急性纤维蛋白性和机化性肺炎的病理学进行综述，并深入探讨与电子烟/蒸气相关肺损伤暴发和当前 SARS-CoV-2 大流行相关的病理特征。
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