Schmid Annina B, Fundaun Joel, Tampin Brigitte
Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, Oxford University, West Wing Level 6, OX3 9DU, Oxford, Großbritannien.
High Country Physical Therapy, Laramie, WY, USA.
Schmerz. 2021 Dec;35(6):419-433. doi: 10.1007/s00482-021-00584-z. Epub 2021 Sep 10.
Entrapment neuropathies such as carpal tunnel syndrome, radiculopathies, or radicular pain are the most common peripheral neuropathies and also the most common cause for neuropathic pain. Despite their high prevalence, they often remain challenging to diagnose and manage in a clinical setting. Summarising the evidence from both preclinical and clinical studies, this review provides an update on the aetiology and pathophysiology of entrapment neuropathies. Potenzial mechanisms are put in perspective with clinical findings. The contemporary assessment is discussed and diagnostic pitfalls highlighted. The evidence for the noninvasive and surgical management of common entrapment neuropathies is summarised and future areas of research are identified.
诸如腕管综合征、神经根病或放射性疼痛等卡压性神经病变是最常见的周围神经病变,也是神经性疼痛最常见的原因。尽管其患病率很高,但在临床环境中,它们的诊断和管理往往仍具有挑战性。本综述总结了临床前和临床研究的证据,提供了关于卡压性神经病变的病因学和病理生理学的最新信息。将潜在机制与临床发现相结合进行探讨。讨论了当代评估方法并强调了诊断陷阱。总结了常见卡压性神经病变的非侵入性和手术治疗的证据,并确定了未来的研究领域。