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链球菌感染后肾小球肾炎患者的可逆性后部脑病综合征:病例报告。

Posterior Reversible Encephalopathy Syndrome in a Patient with Post Streptococcal Glomerulonephritis: A Case Report.

机构信息

Kathmandu Medical College and Teaching Hospital, Sinamangal, Kathmandu, Nepal.

Department of Pediatrics, Kathmandu Medical College and Teaching Hospital, Sinamangal, Kathmandu, Nepal.

出版信息

JNMA J Nepal Med Assoc. 2020 Dec 31;58(232):1072-1074. doi: 10.31729/jnma.5065.

DOI:10.31729/jnma.5065
PMID:34506399
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8028524/
Abstract

Posterior reversible encephalopathy syndrome is a clinical-radiological syndrome neurological disorder with varied symptoms which include headache, visual field defects, seizures, altered consciousness. It is a rare complication of post-streptococcal glomerulonephritis and results in life-threatening manifestations if not managed on time. Although reversible by definition, complications like status epilepticus, intracranial hemorrhage, and ischemic infarction may lead to mortality and morbidity. We report a case of a 9-year-old female patient with posterior reversible encephalopathy syndrome who presented with multiple episodes of seizures and bilateral painless loss of vision for 1 day. Due to her severity, a computed tomography scan was sent which revealed a hypodense lesion in the brain. She was admitted to the pediatric intensive care unit and managed with supportive care for 6 days where she died on the 6th day. Vital signs are simple but important and if overlooked can lead to a series of complicated events.

摘要

后部可逆性脑病综合征是一种具有多种症状的临床-放射学综合征神经系统疾病,包括头痛、视野缺陷、癫痫发作、意识改变。它是链球菌后肾小球肾炎的罕见并发症,如果不及时治疗,会导致危及生命的表现。尽管根据定义是可逆的,但癫痫持续状态、颅内出血和缺血性梗死等并发症可能导致死亡率和发病率。我们报告了一例 9 岁女性患者,患有后部可逆性脑病综合征,表现为多次癫痫发作和双侧无痛性视力丧失 1 天。由于她的病情严重,进行了计算机断层扫描,显示大脑中有一个低密病灶。她被收入儿科重症监护病房,接受了 6 天的支持性治疗,第 6 天死亡。生命体征虽然简单但很重要,如果被忽视,可能会导致一系列复杂的事件。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31af/8028524/542b1abb8fb8/JNMA-58-232-1072-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31af/8028524/5caf9c4a84cf/JNMA-58-232-1072-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31af/8028524/542b1abb8fb8/JNMA-58-232-1072-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31af/8028524/5caf9c4a84cf/JNMA-58-232-1072-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31af/8028524/542b1abb8fb8/JNMA-58-232-1072-g2.jpg

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本文引用的文献

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Clinical and neuroimaging findings in children with posterior reversible encephalopathy syndrome.后部可逆性脑病综合征患儿的临床及神经影像学表现
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Posterior reversible encephalopathy syndrome: clinical and radiological manifestations, pathophysiology, and outstanding questions.后部可逆性脑病综合征:临床和影像学表现、病理生理学及待解决的问题。
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Post-streptococcal glomerulonephritis leading to posterior reversible encephalopathy syndrome: a case report.
链球菌感染后肾小球肾炎导致后部可逆性脑病综合征:一例报告
BMC Res Notes. 2014 Sep 13;7:644. doi: 10.1186/1756-0500-7-644.
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Reversible posterior leucoencephalopathy syndrome in post streptococcal glomerulonephritis.链球菌感染后肾小球肾炎相关可逆性后部白质脑病综合征。
Indian Pediatr. 2010 Mar;47(3):274-6. doi: 10.1007/s13312-010-0037-y.
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A reversible posterior leukoencephalopathy syndrome.可逆性后部白质脑病综合征
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