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肉芽肿性肾炎:幼年发病型结节病的一种罕见表现。

Granulomatous nephritis: A rare presentation of juvenile-onset sarcoidosis.

机构信息

Musculoskeletal Medicine, N.H.L. Municipal Medical College and SVP Hospital, Ahmedabad, Gujarat, India.

Division of Rheumatology, N.H.L. Municipal Medical College and SVP Hospital, Ahmedabad, Gujarat, India.

出版信息

Mod Rheumatol Case Rep. 2022 Jan 7;6(1):111-114. doi: 10.1093/mrcr/rxab011.

Abstract

Sarcoidosis is rare in children. Incidence and prevalence of sarcoidosis in India are not known. Renal involvement in childhood sarcoidosis is further rare with no clear data about prevalence. Here we report a case of a 13-year-old girl who presented with sarcoidosis with multi-system involvement including renal sarcoidosis. She initially presented with pyrexia of unknown origin and cervical lymphadenopathy - evaluation of which led to diagnosis of sarcoidosis. Later, after development of pulmonary involvement, she was treated with oral prednisolone and azathioprine. She again defaulted on medicines and later presented with renal failure and was diagnosed with a renal sarcoidosis. She was treated with oral prednisolone and mycophenolate mofetil with which she gradually improved with normal renal functions.

摘要

结节病在儿童中罕见。印度结节病的发病率和患病率尚不清楚。儿童结节病的肾脏受累更为罕见,关于其患病率也没有明确的数据。在这里,我们报告了一例 13 岁女孩的病例,她患有结节病,多系统受累,包括肾结节病。她最初表现为原因不明的发热和颈部淋巴结肿大-对其进行评估导致了结节病的诊断。后来,在出现肺部受累后,她接受了口服泼尼松龙和硫唑嘌呤治疗。她再次停止用药,后来出现肾衰竭,并被诊断为肾结节病。她接受了口服泼尼松龙和霉酚酸酯治疗,病情逐渐好转,肾功能恢复正常。

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