Department of Nephrology, Narayana Medical College, Nellore, Andhra Pradesh, India.
Advanced Research Center (Genetics), Narayana Medical College, Nellore, Andhra Pradesh, India.
Saudi J Kidney Dis Transpl. 2020 Mar-Apr;31(2):549-552. doi: 10.4103/1319-2442.284036.
Sarcoidosis is a systemic disease characterized by non caseating granulomatous inflammation. Sarcoidosis can affect any organ, but it most commonly involves the lungs and lymph nodes. The exact incidence of renal involvement in sarcoidosis remains unclear, but it is found to be rare. Granulomatous interstitial nephritis is the most common histological pattern, but its presentation with renal insufficiency is rare. Here, we present a case of sarcoidosis causing granulomatous interstitial nephritis presenting as isolated non oliguric acute renal failure.
结节病是一种以非干酪样肉芽肿性炎症为特征的系统性疾病。结节病可累及任何器官,但最常累及肺部和淋巴结。结节病累及肾脏的确切发病率尚不清楚,但发现较为罕见。肉芽肿性间质性肾炎是最常见的组织学类型,但以肾功能不全为表现者少见。本文报道 1 例结节病引起的肉芽肿性间质性肾炎,表现为孤立性非少尿性急性肾衰竭。