Superinfection exclusion and changes in cellular transport processes in phage infected Salmonella typhimurium.

The changes induced by bacteriophage P22 in the cellular transport process(es) of the host Salmonella typhimurium (Taneja et al., 1975; Khandekar et al., 1975; Bandyopadhyay and Chakravorty, 1976) involve interactions between the superinfection exclusion system of the resident prophage and the C immunity region of the superinfecting phage. The sie A gene of the prophage interferes with the changes in the cellular transport process induced by the superinfecting phage. However, if the superinfecting phage carries active C1 and C2 genes there is no such interference. Thus the C1 and C2 genes of the superinfecting phage seem to be expressed in the sieA+ lysogen.