IRCSS Fondazione Don Carlo Gnocchi, Via Capecelatro, 66-20148, Milano, Italy.
U.O. Clinica Neurologica, III Ospedale San Paolo Via Antonio di Rudini 8, 20142, Milano, Italy.
Gait Posture. 2021 Oct;90:210-214. doi: 10.1016/j.gaitpost.2021.08.024. Epub 2021 Aug 28.
The minimal clinically important difference (MCID) of modified Dynamic Gait Index (mDGI) has not yet been determined for People with Neurological Disorders (PwND).
To establish the MCID of the mDGI to determine clinically meaningful improvement in balance and gait in PwND.
In this longitudinal study from a randomised clinical trial, 55 participants both in and outpatients with neurological disorders, received fifteen 40-minute rehabilitation sessions. Inpatients received daily treatments over a period of three weeks while outpatients received three treatments/week over a period of five weeks. An anchor-based method using percentage rating of improvement in balance (Activities Balance Confidence scale, ABC) was used to determine the MCID of mDGI. The MCID was defined as the minimum change in mDGI total score (post - pre intervention) that was needed to perceive at least a 10 % improvement on the ABC scale. A Receiver Operating Characteristic curve was used to define the cut-off for the optimal MCID of the mDGI discriminating between improved and not improved participants.
The MCID of the mDGI total score was 6 points and Area under the Curve was 0.64. For the mDGI time sub-scores the MCID was 2 points and Area under the Curve was 0.6.
The MCID of balance and gait improvement measured by mDGI was prudently establish at ≥7 points, meaning that this is the minimum improvement score PwND need to get to perceive a clinically relevant change in their balance and gait confidence. These reference values can be a tool incorporated into clinicians daily practice to interpret mDGI change scores helping to determine whether the intervention is effective; to develop clinical tailored intervention goals and to establish meaningful perceived change in PwND.
改良动态步态指数(mDGI)的最小临床重要差异(MCID)尚未确定用于神经障碍患者(PwND)。
确定 mDGI 的 MCID,以确定 PwND 的平衡和步态有临床意义的改善。
在这项来自随机临床试验的纵向研究中,55 名门诊和住院的神经障碍患者接受了 15 次 40 分钟的康复治疗。住院患者在三周内接受每日治疗,而门诊患者在五周内每周接受三次治疗。使用基于锚定的方法,即平衡改善的百分比评分(活动平衡信心量表,ABC),来确定 mDGI 的 MCID。MCID 定义为 mDGI 总分(干预后-干预前)的最小变化,需要在 ABC 量表上至少提高 10%才能感知到。使用接收者操作特征曲线来定义区分改善和未改善参与者的 mDGI 最佳 MCID 的截止值。
mDGI 总分的 MCID 为 6 分,曲线下面积为 0.64。对于 mDGI 时间子评分,MCID 为 2 分,曲线下面积为 0.6。
mDGI 测量的平衡和步态改善的 MCID 谨慎地确定为≥7 分,这意味着这是 PwND 需要获得的最小改善分数,以感知到他们的平衡和步态信心的临床相关变化。这些参考值可以作为一种工具纳入临床医生的日常实践中,解释 mDGI 变化分数,以帮助确定干预是否有效;为临床定制干预目标,并确定 PwND 中感知到的有意义的变化。