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心脏再同步治疗和心脏收缩力调节在晚期心力衰竭患者中的应用:如何选择合适的患者?

Cardiac Resynchronization Therapy and Cardiac Contractility Modulation in Patients with Advanced Heart Failure: How to Select the Right Candidate?

机构信息

Division of Cardiovascular Medicine, 473 West 12th Avenue, Suite 200, Columbus, OH 43065, USA.

出版信息

Heart Fail Clin. 2021 Oct;17(4):599-606. doi: 10.1016/j.hfc.2021.05.005.

DOI:10.1016/j.hfc.2021.05.005
PMID:34511208
Abstract

Cardiac resynchronization therapy is a well-established treatment of heart failure with reduced left ventricular ejection fraction and a wide QRS complex. Cardiac contractility modulation therapy is an emerging electrical treatment indicated for use in patients with symptomatic heart failure caused by moderate-to-severe systolic left ventricular dysfunction (left ventricular ejection fraction ranging from 25% to 45%), with no indication for cardiac resynchronization therapy. Cardiac contractility modulation therapy improves functional status, exercise capacity, quality of life, and possibly prevents hospital admissions in indicated patients. An algorithm for patient selection for these two forms of electrical therapy for heart failure is presented.

摘要

心脏再同步治疗是一种成熟的心力衰竭治疗方法,适用于左心室射血分数降低和宽 QRS 复合物的心力衰竭患者。心脏收缩力调节治疗是一种新兴的电治疗方法,适用于由中度至重度收缩性左心室功能障碍(左心室射血分数在 25%至 45%之间)引起的有症状心力衰竭且不适合心脏再同步治疗的患者。心脏收缩力调节治疗可改善患者的功能状态、运动能力、生活质量,并可能预防有适应证的患者住院。本文提出了这两种心力衰竭电治疗方法的患者选择算法。

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Cardiac Resynchronization Therapy and Cardiac Contractility Modulation in Patients with Advanced Heart Failure: How to Select the Right Candidate?心脏再同步治疗和心脏收缩力调节在晚期心力衰竭患者中的应用:如何选择合适的患者?
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引用本文的文献

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Device-therapy in chronic heart failure: Cardiac contractility modulation versus cardiac resynchronization therapy.慢性心力衰竭的器械治疗:心脏收缩力调制与心脏再同步治疗
ESC Heart Fail. 2025 Feb;12(1):456-466. doi: 10.1002/ehf2.15067. Epub 2024 Sep 29.
2
Novel Medical Treatments and Devices for the Management of Heart Failure with Reduced Ejection Fraction.用于治疗射血分数降低的心力衰竭的新型医学疗法和设备。
J Cardiovasc Dev Dis. 2024 Apr 19;11(4):125. doi: 10.3390/jcdd11040125.
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Enhancing myocardial function with cardiac contractility modulation: potential and challenges.
通过心肌收缩力调节增强心肌功能:潜力与挑战。
ESC Heart Fail. 2024 Feb;11(1):1-12. doi: 10.1002/ehf2.14575. Epub 2023 Nov 10.
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Use of Cardiac Contractility Modulation as Bridge to Transplant in an Obese Patient With Advanced Heart Failure: A Case Report.心脏收缩力调制在一名晚期心力衰竭肥胖患者中作为移植桥梁的应用:病例报告
Front Cardiovasc Med. 2022 Feb 16;9:833143. doi: 10.3389/fcvm.2022.833143. eCollection 2022.