Unit of Cardiovascular Science, Campus Bio-Medico University of Rome, Rome, Italy.
Unit of Cardiovascular Science, Campus Bio-Medico University of Rome, Rome, Italy.
Heart Fail Clin. 2021 Oct;17(4):635-646. doi: 10.1016/j.hfc.2021.05.008. Epub 2021 Jul 24.
Patients with advanced heart failure (AdHF) have a reduced quality of life and poor prognosis. A heart transplant (HT) is an effective treatment for such patients. Still, because of a shortage of donor organs, the final decision to place a patient without contraindications on the HT waiting list is based on detailed risk-benefit analysis. Cardiopulmonary exercise tests (CPETs) play a pivotal role in guiding selection in patients with AdHF considered for an HT. Furthermore, several validated multivariable predicting scores obtained through various techniques, including the CPETs, are available and part of the decision-making process for HT listing.
患有晚期心力衰竭(AdHF)的患者生活质量降低,预后不良。心脏移植(HT)是此类患者的有效治疗方法。然而,由于供体器官短缺,最终决定将无禁忌症的患者列入 HT 等待名单是基于详细的风险效益分析。心肺运动试验(CPETs)在指导考虑进行 HT 的 AdHF 患者的选择方面发挥着关键作用。此外,还可以使用通过包括 CPET 在内的各种技术获得的几种经过验证的多变量预测评分,并将其作为 HT 列表决策过程的一部分。