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初次及翻修全关节置换术后仍接受输血的是哪些人?

Who Is Still Receiving Blood Transfusions After Primary and Revision Total Joint Arthroplasty?

作者信息

DeMik David E, Carender Christopher N, Glass Natalie A, Brown Timothy S, Callaghan John J, Bedard Nicholas A

机构信息

Department of Orthopedics and Rehabilitation, University of Iowa, Iowa City, IA.

出版信息

J Arthroplasty. 2022 Jun;37(6S):S63-S69.e1. doi: 10.1016/j.arth.2021.08.018. Epub 2021 Aug 25.

Abstract

BACKGROUND

Incidence of blood transfusions after primary and revision total hip and knee arthroplasty (primary total hip arthroplasty [pTHA], revision THA [rTHA], primary total knee arthroplasty [pTKA], and revision TKA [rTKA]) has been decreasing for a multitude of reasons. The purpose of this study was to assess whether transfusion rates have continued to decline and evaluate patient factors associated with transfusions.

METHODS

The American College of Surgeons National Surgical Quality Improvement Program was queried to identify patients undergoing pTHA, pTKA, rTHA, and rTKA between 2011 and 2019. Patients undergoing bilateral procedures and arthroplasty for fracture, infection, or tumor were excluded. Trends in blood transfusions were assessed. Patient factor association with blood transfusions was evaluated using 2018 and 2019 data.

RESULTS

Transfusion rates decreased from 21.4% in 2011 to 2.5% in 2019 for pTHA (P < .0001). For pTKA, transfusion rates declined from 17.6% to 0.7% (P < .0001). In rTHA, the transfusion rate decreased from 33.5% to 12.0% from 2011 to 2019 (P < .0001). Transfusion rates declined from 19.4% to 2.6% for rTKA during the study period (P < .0001). Transfusions were more frequent in patients who were older, female, with more comorbidities, with lower hematocrit, receiving nonspinal anesthesia, and with longer operative time. Lower preoperative hematocrit, history of bleeding disorders, and preoperative transfusion were associated with greater odds for postoperative transfusion after multivariate analysis.

CONCLUSION

Transfusions after both primary and revision total joint arthroplasty have continued to decrease. Studies of arthroplasty complications should account for decreasing transfusions when assessing overall complication rates. Future studies should consider interventions to further reduce transfusions in revision arthroplasty.

摘要

背景

由于多种原因,初次及翻修全髋关节和膝关节置换术后(初次全髋关节置换术[pTHA]、翻修全髋关节置换术[rTHA]、初次全膝关节置换术[pTKA]和翻修全膝关节置换术[rTKA])输血发生率一直在下降。本研究的目的是评估输血率是否持续下降,并评估与输血相关的患者因素。

方法

查询美国外科医师学会国家外科质量改进计划,以确定2011年至2019年间接受pTHA、pTKA、rTHA和rTKA的患者。排除接受双侧手术以及因骨折、感染或肿瘤而行关节置换术的患者。评估输血趋势。使用2018年和2019年的数据评估患者因素与输血的相关性。

结果

pTHA的输血率从2011年的21.4%降至2019年的2.5%(P <.0001)。对于pTKA,输血率从17.6%降至0.7%(P <.0001)。在rTHA中,2011年至2019年输血率从33.5%降至12.0%(P <.0001)。在研究期间,rTKA的输血率从19.4%降至2.6%(P <.0001)。年龄较大、女性、合并症较多、血细胞比容较低、接受非脊髓麻醉以及手术时间较长的患者输血更为频繁。多因素分析显示,术前血细胞比容较低、有出血性疾病史和术前输血与术后输血的几率更高相关。

结论

初次及翻修全关节置换术后的输血率持续下降。关节置换术并发症研究在评估总体并发症发生率时应考虑到输血率的下降。未来的研究应考虑采取干预措施,以进一步减少翻修关节置换术中的输血。

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