Berghout E
Mobile Eye Clinic, Bawku Hospital.
Trop Geogr Med. 1987 Oct;39(4):323-9.
The ocular findings in the male population of 3 villages from a hyperendemic area of onchocerciasis in North Ghana have been recorded. Vector control in the Volta River Basin has led to reduced microfilarial loads and improved tolerance of treatment with diethylcarbamazine-citrate (DEC-C). Prevalence of posterior eye lesions increased sharply above the age of 30 years in the survey population. In patients with palpable onchocercomas (nodules) serious pathology of the posterior segment of the eye was found twice as frequently as in onchocerciasis patients without nodules. In the village visited by the Mobile Eye Team since 1978 the prevalence of serious eye lesions was slightly lower than in the two villages never visited by the eye team. Desirability to give treatment to the younger population with low incidence of serious eye lesions is expressed. Attention is drawn to the increased danger of adverse reactions to treatment in the presence of posterior eye lesions.
在加纳北部盘尾丝虫病高度流行地区的3个村庄的男性人群中记录了眼部检查结果。沃尔特河流域的病媒控制已导致微丝蚴负荷降低，并提高了对枸橼酸乙胺嗪（DEC-C）治疗的耐受性。在调查人群中，30岁以上后眼部病变的患病率急剧上升。在可触及盘尾丝虫瘤（结节）的患者中，眼后段严重病变的发生率是无结节的盘尾丝虫病患者的两倍。自1978年以来流动眼科医疗队到访过的村庄中，严重眼部病变的患病率略低于该医疗队从未到访过的两个村庄。文中表达了为严重眼部病变发病率较低的年轻人群提供治疗的意愿。文中还提请注意存在后眼部病变时治疗不良反应的风险增加。
