Department of Life Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Physiology (Bethesda). 2022 Mar 1;37(2):55-68. doi: 10.1152/physiol.00006.2021. Epub 2021 Sep 13.
Despite numerous studies of immune sexual dimorphism, sexual differences are not rigorously mapped and dimorphic mechanisms are incompletely understood. Current immune research typically studies sex differences in specific cells, tissues, or diseases but without providing an integrated picture. To connect the dots, we suggest comprehensive research approaches to better our understanding of immune sexual dimorphism and its mechanisms.
尽管有大量关于免疫性别二态性的研究,但性别差异并未得到严格映射,且二态性机制也未被完全理解。目前的免疫研究通常针对特定细胞、组织或疾病中的性别差异进行研究,但并未提供整体图景。为了将这些点联系起来,我们建议采用全面的研究方法,以更好地理解免疫性别二态性及其机制。