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Conn 综合征手术治疗的作用——一例醛固酮分泌腺瘤所致难治性高血压病例

The role of surgery in Conn's syndrome - a case of refractory hypertension secondary to an aldosterone secreting adenoma.

机构信息

Medical Outpatient Department, Bertha Gxowa Hospital, South Africa.

Department of Surgery, Charlotte Maxeke Johannesburg Academic Hospital, South Africa.

出版信息

S Afr J Surg. 2021 Sep;59(3):131a-131c.

Abstract

Primary aldosteronism, eponymously known as Conn's syndrome, has recently gained recognition as the most common cause of endocrine hypertension. Unilateral subtypes, such as aldosterone secreting adenomas, are managed surgically and are potentially curable. The background of refractory hypertension and hypokalaemia in a forty-year-old man raised suspicions of Conn's syndrome which was localised to an aldosterone secreting adenoma in the right adrenal gland. The patient underwent a laparoscopic intraperitoneal right adrenalectomy which resulted in normalisation of his plasma aldosterone concentration as well as improved blood pressure control.

摘要

原发性醛固酮增多症,又称 Conn 综合征,最近被认为是内分泌性高血压最常见的病因。单侧亚型,如醛固酮分泌腺瘤,可通过手术治疗,具有潜在的治愈可能。一位 40 岁男性的难治性高血压和低钾血症背景引起了对 Conn 综合征的怀疑,该综合征定位于右侧肾上腺的醛固酮分泌腺瘤。患者接受了腹腔镜腹膜内右侧肾上腺切除术,导致其血浆醛固酮浓度正常化,并改善了血压控制。

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