School of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang 212013, PR China.
School of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, PR China.
Analyst. 2021 Sep 13;146(18):5747-5755. doi: 10.1039/d1an01200b.
A super simple ratiometric fluorescence nanosensor has been fabricated by controlling the ligands of CdZnTe quantum dots (QDs), allowing the sensitive and visual detection of silver ions (Ag). The green-emitting L-cysteine-protected CdZnTe QDs (Lcys-CdZnTe QDs) had a specific response to Ag and were used as the reporting probe, while the red-emitting -acetyl-L-cysteine-protected CdZnTe QDs (NAC-CdZnTe QDs) showed no obvious response to all tested metal ions and were selected as the reference probe. Simply mixing them without any encapsulated synthesis ultimately produced a time-saving, low-cost detection method, allowing the sensitive and visual detection of Ag in samples. The proposed nanosensor exhibited a linear range of 0.5-4.0 μM along with a detection limit of 0.17 μM, and has been successfully applied in real tap water and lake water samples. This nanosensor also showed obvious color changes in the detection process and has potential in visual semi-quantitative detection. Our approach may provide a general and feasible strategy for designing ratiometric fluorescence nanosensors, which will attract a wide range of interest in sensing-related fields.
一种超简单的比率荧光纳米传感器已被制备出来，通过控制 CdZnTe 量子点 (QDs) 的配体，实现了对银离子 (Ag) 的灵敏可视化检测。发绿光的 L-半胱氨酸保护的 CdZnTe QDs（Lcys-CdZnTe QDs）对 Ag 有特定的响应，被用作报告探针，而发红光的 N-乙酰-L-半胱氨酸保护的 CdZnTe QDs（NAC-CdZnTe QDs）对所有测试的金属离子都没有明显的响应，被选为参考探针。简单地混合它们而无需任何封装合成，最终产生了一种节省时间、低成本的检测方法，能够对样品中的 Ag 进行灵敏可视化检测。所提出的纳米传感器在 0.5-4.0 μM 的线性范围内具有检测限为 0.17 μM，并已成功应用于实际自来水和湖水样品中。该纳米传感器在检测过程中还表现出明显的颜色变化，在可视化半定量检测方面具有潜力。我们的方法可能为设计比率荧光纳米传感器提供一种通用且可行的策略，这将在传感相关领域引起广泛关注。
