纳米纤维素的季铵化功能化及其作为抗菌剂的评估。
Functionalization of nanocellulose to quaternized nanocellulose tri-iodide and its evaluation as an antimicrobial agent.
机构信息
Department of Chemistry, Himachal Pradesh University, Summer Hill, Shimla 171005, India.
Department of Chemistry, Himachal Pradesh University, Summer Hill, Shimla 171005, India.
出版信息
Int J Biol Macromol. 2021 Nov 1;190:1007-1014. doi: 10.1016/j.ijbiomac.2021.08.228. Epub 2021 Sep 10.
The reported research involves formation of quaternized nanocellulose triiodide for use as an agent for controlled release of iodine. Nanocellulose was extracted from bagasse and the extracted cellulose nanofibers (CNFs) were quaternized with 3-chloro-2-hydroxypropyltrimethyl ammonium chloride (CHPTAC) in NaOH/urea solution. This was followed by exchange of Cl with I by reaction with KI/I. Nanofibers having I anions were characterized by SEM, TEM, XRD, XRF and FTIR spectroscopy. The iodine content was estimated to be 33.42% and the fibers showed no leaching of molecular I in detectable amounts. The fibers showed a maximum activity of 94.73% and 99.86% against E. coli and S. aureus, respectively. These are capable of sustaining 100% antimicrobial activity over a period of six months. These fibers can thus find potential applications as a disinfectant agent in biomedical and water purification processes.
所报道的研究涉及季铵化纳米纤维素三碘化碘的形成，用作碘的控制释放剂。纳米纤维素是从甘蔗渣中提取的，提取的纤维素纳米纤维（CNF）在 NaOH/尿素溶液中用 3-氯-2-羟丙基三甲基氯化铵（CHPTAC）季铵化。然后通过与 KI/I 反应将 Cl 与 I 交换。通过 SEM、TEM、XRD、XRF 和 FTIR 光谱对具有 I 阴离子的纳米纤维进行了表征。碘含量估计为 33.42%，纤维中未检测到分子 I 的明显浸出。这些纤维对大肠杆菌和金黄色葡萄球菌的最大活性分别为 94.73%和 99.86%。这些纤维在六个月的时间内能够持续保持 100%的抗菌活性。因此，这些纤维可以作为生物医学和水净化过程中的消毒剂在潜在应用。
Zotero 插件