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能否预测胶囊内镜检查不完整?应用逻辑回归模型的多变量分析结果。

Can we predict an incomplete capsule endoscopy? Results of a multivariate analysis using a logistic regression model.

机构信息

Gastroenterology, Complejo Hospitalario de Navarra, España.

Gastroenterology, Complejo Hospitalario de Navarra.

出版信息

Rev Esp Enferm Dig. 2022 Jun;114(6):329-334. doi: 10.17235/reed.2021.7320/2020.

DOI:10.17235/reed.2021.7320/2020
PMID:34517709
Abstract

BACKGROUND AND AIMS

small bowel capsule endoscopy (SBCE) does not reach the cecum within the battery lifetime in approximately 15-35 % of patients. Incomplete examinations result in diagnostic delays and increase the economic burden. To date, risk factors for incomplete examinations have been described with contradictory results. The aims of this study were to analyze the rate and identify risk factors for incomplete examinations, excluding capsule retentions, in a large cohort of patients.

METHODS

data from 1,894 consecutive SBCE examinations performed from January 2009 to December 2015 were analyzed. Variables recorded included demographics, past medical and surgical history, biochemical parameters and procedure characteristics. The rate of incomplete examinations, excluding capsule retentions, was calculated and a multivariate analysis using a logistic regression model was performed in order to evaluate predictive factors.

RESULTS

the incidence of incomplete examinations, excluding capsule retentions, was 10.1 % (187 incomplete procedures). The multivariate analysis showed that age > 65 years, gastric transit time > 41 minutes and SB transit time > 286 minutes are predictive factors for incomplete examinations, increasing the probability of this event by 199 % (OR: 1.99; 95 % CI: 1.34-2.95), 260 % (OR: 2.60; 95 % CI: 1.72-3.93) and 352 % (OR: 3.52; 95 % CI: 2.26-5.48), respectively.

CONCLUSIONS

age > 65 years, gastric transit time > 41 minutes and SB transit time > 286 minutes are predictive factors for incomplete examinations excluding capsule retentions. Both age and gastric transit time events are known before the procedure ends. Therefore, pharmacologic or endoscopic measures may be taken into account to avoid incomplete examinations.

摘要

背景与目的

小肠胶囊内镜(SBCE)在大约 15-35%的患者中,其电池寿命内无法到达盲肠。不完整的检查会导致诊断延迟,并增加经济负担。迄今为止,已经描述了不完全检查的危险因素,但结果存在矛盾。本研究的目的是分析在一个大的患者队列中,排除胶囊滞留的情况下,不完全检查的发生率并确定其危险因素。

方法

分析了 2009 年 1 月至 2015 年 12 月期间进行的 1894 例连续 SBCE 检查的数据。记录的变量包括人口统计学、既往内科和外科病史、生化参数和程序特征。计算了排除胶囊滞留的不完全检查率,并采用逻辑回归模型进行了多变量分析,以评估预测因素。

结果

排除胶囊滞留的不完全检查发生率为 10.1%(187 例不完全检查)。多变量分析显示,年龄>65 岁、胃转运时间>41 分钟和 SB 转运时间>286 分钟是不完全检查的预测因素,使该事件的发生概率分别增加 199%(OR:1.99;95%CI:1.34-2.95)、260%(OR:2.60;95%CI:1.72-3.93)和 352%(OR:3.52;95%CI:2.26-5.48)。

结论

年龄>65 岁、胃转运时间>41 分钟和 SB 转运时间>286 分钟是排除胶囊滞留的不完全检查的预测因素。年龄和胃转运时间事件在检查结束前已知。因此,可以考虑采取药物或内镜措施来避免不完全检查。

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