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皮肤科免疫抑制和免疫调节治疗与 2019 年冠状病毒病(COVID-19)。

Immunosuppressive and immunomodulatory therapies in dermatology and coronavirus disease 2019 (COVID-19).

机构信息

Department of Dermatology, Skin and Stem Cell Research Center, Tehran University of Medical Sciences, Tehran, Iran.

Department of Dermatology, Skin and Stem Cell Research Center, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

Clin Dermatol. 2021 May-Jun;39(3):517-520. doi: 10.1016/j.clindermatol.2021.01.003. Epub 2021 Feb 16.

DOI:10.1016/j.clindermatol.2021.01.003
PMID:34518013
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7884222/
Abstract

COVID-19 infection may affect the individuals with many underlying conditions including skin diseases. This cross-sectional study was conducted to provide an overview regarding the prevalence of COVID-19 disease in the patients with several skin diseases. Overall, 703 patients with several skin diseases participated in the study and completed our online-designed questionnaire. Among the total participants, only 32(4.6%) subjects reported the COVID-19 infection. The prevalence rate was equal to 0.04%. In the patients with psoriasis, 14 out of 322 people (4.3%) developed the COVID-19. Three out of 159 patients (1.9%) with alopecia areata had been affected with the COVID-19 and 4 (5.2%) patients with vitiligo had caught the disease. Only one subject (2%) with the lichen planus, and 6 (6.8%) patients with other skin diseases had developed the COVID-19 but in the patients with GVHD (Graft Versus Host Disease), 4 (80%) out of 5 patients had caught the COVID-19 disease. The frequency of COVID-19 infection was low in the studied population however; more studies with larger sample size are needed to determine the exact prevalence of the infection in the patients with skin diseases undergoing the treatment with several systemic medications.

摘要

COVID-19 感染可能会影响许多患有基础疾病的个体,包括皮肤病患者。本横断面研究旨在概述几种皮肤病患者中 COVID-19 疾病的患病率。共有 703 名患有几种皮肤病的患者参与了这项研究,并完成了我们在线设计的问卷。在所有参与者中,只有 32 名(4.6%)报告了 COVID-19 感染。患病率等于 0.04%。在银屑病患者中,322 人中 14 人(4.3%)感染了 COVID-19。159 名斑秃患者中有 3 人(1.9%)感染了 COVID-19,4 名(5.2%)白癜风患者感染了 COVID-19。只有 1 名(2%)扁平苔藓患者和 6 名(6.8%)其他皮肤病患者感染了 COVID-19,但在 GVHD(移植物抗宿主病)患者中,5 名患者中有 4 名(80%)感染了 COVID-19。在研究人群中,COVID-19 感染的频率较低;然而,需要进行更多具有更大样本量的研究,以确定正在接受多种系统性药物治疗的皮肤病患者中感染的确切患病率。