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奥克兰的头颈部黑色素瘤

Melanoma of the head and neck in Auckland.

作者信息

Douglas R G, Shaw J H

机构信息

University Department of Surgery, Auckland Hospital.

出版信息

N Z Med J. 1987 Sep 23;100(832):584-7.

PMID:3452099
Abstract

A series of 154 cases of malignant melanoma of the head and neck has been studied retrospectively, representing a subgroup of 972 cases of all sites seen over a 15-year period. There was no significant difference in the mean level of invasion as defined by Clark between head and neck melanomas and lesions of other sites. The primary lesion was most commonly situated on the face and one third of the tumours arose in Hutchison's melanotic freckles. The 5-year survival rate was 59% and the rate of local recurrence 8%. The mean histologically defined closest margin of dissection was 0.7 cm and only three patients underwent prophylactic lymph node resection. The margin of excision did not influence mortality, but if thick lesions were not excised widely then there was an increase in local recurrence. Our results suggest that a more conservative surgical approach may be feasible in selected patients with melanoma of the head and neck.

摘要

对154例头颈部恶性黑色素瘤病例进行了回顾性研究,这些病例是15年期间所见的972例所有部位恶性黑色素瘤病例中的一个亚组。根据克拉克(Clark)所定义的浸润程度,头颈部黑色素瘤与其他部位病变之间在平均浸润水平上无显著差异。原发灶最常见于面部,三分之一的肿瘤发生于哈钦森(Hutchison)黑素雀斑。5年生存率为59%,局部复发率为8%。组织学确定的平均最近切缘为0.7厘米,仅3例患者接受了预防性淋巴结切除。切除切缘不影响死亡率,但如果厚病变未广泛切除,则局部复发会增加。我们的结果表明,对于某些头颈部黑色素瘤患者,采用更保守的手术方法可能是可行的。

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