Departamento de Pediatría, Hospital Nacional Edgardo Rebagliati Martins, Lima, Peru.
Facultad de Medicina, Universidad Nacional Federico Villarreal, Lima, Peru.
BMJ Case Rep. 2021 Sep 14;14(9):e244768. doi: 10.1136/bcr-2021-244768.
SARS-CoV-2 infection in children with primary immunodeficiency disease (PID) and its complications have not yet been well described, the course of COVID-19 can range from mild illness to death. We aim to report the case of a child with a PID who develop a severe and persistent pulmonary COVID-19 infection. We present chronologically his clinical course, tests, interventions and radiological findings showing his irregular evolution and poor response to infection. This case highlights the need to accurately monitor the immune response in these cases to try to stop the progression of the damage.
儿童原发性免疫缺陷病(PID)合并 SARS-CoV-2 感染及其并发症尚未得到充分描述,COVID-19 的病程范围从轻症到死亡。我们旨在报告一例 PID 儿童发生严重和持续的肺部 COVID-19 感染的病例。我们按时间顺序介绍他的临床过程、检查、干预措施和放射学发现,这些发现显示了他的病情演变不规则和对感染的反应不佳。这个病例强调了需要准确监测这些病例的免疫反应,以试图阻止损害的进展。