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[1例采用 CapeOX、S-1 及手术治疗的残胃癌肝转移长期生存病例]

[A Long-Term Survival Case of Liver Metastasis from Remnant Gastric Cancer Treated by CapeOX, S-1, and Surgery].

作者信息

Satoh Ken, Nakamura Hiroaki, Nakamura Jun, Iyama Akihiro

机构信息

Dept. of Surgery, Yuaikai Foundation and Oda Hospital.

出版信息

Gan To Kagaku Ryoho. 2021 Sep;48(9):1173-1175.

Abstract

A 70-year-old man, who had undergone distal gastrectomy for early gastric cancer at 63-year-old, had multiple liver metastases from remnant gastric cancer, which was diagnosed as cT3(SS), N0, M1, cStage Ⅳ. After a regimen consisting of 8 courses of capecitabine plus oxaliplatin and 2 courses of S-1 was administered, clinical CR was confirmed for the remnant gastric cancer and multiple liver metastases. Chemotherapy was administered for 10 months and discontinued for side effects and the needs of the patient. Anticoagulant drugs were administered for the onset of cerebral infarction after he vomited blood. A gastric ulcer in the oral side of the anastomotic portion was detected and diagnosed as poorly differentiated adenocarcinoma. Multiple liver metastases could not be detected by PET-CT, and we performed a total gastrectomy of the remnant stomach. The patient remains relapse-free 4 years and 10 months after chemotherapy(3 years and 10 months after discontinuing chemotherapy).

摘要

一名70岁男性,63岁时因早期胃癌接受了远端胃切除术,现出现残胃癌多发肝转移,诊断为cT3(SS)、N0、M1、cStage Ⅳ期。在接受了8个疗程的卡培他滨加奥沙利铂及2个疗程的S-1治疗方案后,残胃癌及多发肝转移灶经确认达到临床完全缓解(CR)。化疗进行了10个月,因副作用及患者自身需求而停药。患者在吐血后发生脑梗死,遂给予抗凝药物治疗。在吻合口口腔侧检测到胃溃疡,诊断为低分化腺癌。PET-CT未检测到多发肝转移,于是我们对残胃实施了全胃切除术。化疗后4年10个月(停止化疗后3年10个月),患者仍无复发。

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