Jiang James Yuheng, Liang Yip Joshua Wei, Kang Christine, Tran Vu Hoang, Lee Marco Enoch, Le Ken, Mansberg Robert
Department of Nuclear Medicine and PET, Nepean Hospital, Kingswood, New South Wales, Australia.
Faculty of Medicine and Health, University of Sydney, New South Wales, Sydney, Australia.
Radiol Case Rep. 2021 Sep 4;16(11):3422-3425. doi: 10.1016/j.radcr.2021.08.014. eCollection 2021 Nov.
A 70-year-old gentleman with a history of Gleason score 7 (3 + 4) prostate adenocarcinoma was treated with radical prostatectomy with clear surgical margins. Postoperatively his prostate specific antigen was undetectable. However, his prostate specific antigen was slowly rising and he was referred for a Galium-Prostate Specific Membrane Antigen (PSMA) PET/CT scan. Findings were suggestive of local prostatic cancer recurrence with no evidence of nodal or distant metastasis. An incidental PSMA avid focus was noted in the left frontal lobe, inseparable from the left frontal bone laterally. Subsequent MRI findings were consistent with meningioma. Meningioma is the most common primary brain tumor and may be a cause of false positive prostate cancer metastasis due to Ga-PSMA uptake.
一位70岁男性，有Gleason评分7（3 + 4）的前列腺腺癌病史，接受了根治性前列腺切除术，手术切缘清晰。术后他的前列腺特异性抗原检测不到。然而，他的前列腺特异性抗原在缓慢上升，因此他被转诊进行镓-前列腺特异性膜抗原（PSMA）PET/CT扫描。检查结果提示前列腺癌局部复发，无淋巴结或远处转移迹象。在左侧额叶发现一个偶然的PSMA摄取灶，与左侧额骨外侧无法区分。随后的MRI检查结果与脑膜瘤一致。脑膜瘤是最常见的原发性脑肿瘤，可能是由于Ga-PSMA摄取导致前列腺癌转移假阳性的原因。
