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舌下涎腺黏液表皮样癌:1例罕见病例报告

Mucoepidermoid Carcinoma of Sublingual Salivary Gland: A Rare Case Report.

作者信息

Sankar K, Vasupradha G, Jaipal N

机构信息

Department of Oral and Maxillofacial Surgery, Mahatma Gandhi Post Graduate Institute of Dental Sciences, Puducherry, India.

Department of Oral Pathology, Adhiparasakthi Dental College and Hospital, Melmaruvathur, Tamil Nadu, India.

出版信息

Ann Maxillofac Surg. 2021 Jan-Jun;11(1):183-186. doi: 10.4103/ams.ams_252_20. Epub 2021 Feb 19.

Abstract

RATIONALE

Sublingual salivary gland tumours are very rare but are mostly malignant. As very limited literature is available, we present a rare case of mucoepidermoid carcinoma (MEC) of sublingual salivary gland.

PATIENT CONCERNS

A56-year-old female presented with an asymptomatic swelling of 15-year duration in the floor of the mouth and chin region.

DIAGNOSIS

Mandibular occlusal view, computed tomography scan, and ultrasonogram revealed calcification and the tumour to be of salivary origin. Incisional biopsy showed clear cell changes.

TREATMENT

The sublingual and submandibular salivary gland along with the associated nodes was excised through transoral approach with midline osteotomy.

OUTCOMES

The histopathologic diagnosis of excised specimen was "Intermediate grade MEC" with clear cell changes, stromal hyalinization, and local invasion. The patient was followed up for 12 months, and there was no evidence of any recurrence.

TAKEAWAY LESSONS

Sublingual salivary gland malignancies show early invasion and a higher rate of metastases, thus requiring a vigilant intervention.

摘要

理论依据

舌下涎腺肿瘤非常罕见,但大多为恶性。由于相关文献非常有限,我们报告一例罕见的舌下涎腺黏液表皮样癌(MEC)病例。

患者情况

一名56岁女性,口底和颏部出现持续15年的无症状肿胀。

诊断

下颌咬合片、计算机断层扫描和超声检查显示有钙化,肿瘤起源于涎腺。切开活检显示有透明细胞改变。

治疗

通过经口入路并进行中线截骨术切除舌下和下颌下涎腺及相关淋巴结。

结果

切除标本的组织病理学诊断为“中度MEC”,伴有透明细胞改变、间质玻璃样变性和局部浸润。对患者进行了12个月的随访,没有任何复发迹象。

经验教训

舌下涎腺恶性肿瘤表现为早期浸润和较高的转移率,因此需要警惕并进行干预。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b003/8407638/4bb33523bf17/AMS-11-183-g001.jpg

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