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新生儿期先天性髂动脉瘤的显微外科和血管内治疗:两例报告及文献复习

Microsurgical and Endovascular Management of Congenital Iliac Aneurysms in the Neonatal Period: Two Cases and a Literature Review.

作者信息

Iyer Hari, Joharifard Shahrzad, Le-Nguyen Annie, Dubois Josée, Ghali Rafik, Borsuk Daniel E, Lallier Michel

机构信息

Department of Surgery, Division of Plastic & Reconstructive Surgery, Université de Montréal, Montréal, Québec, Canada.

Department of Surgery, Division of Paediatric Surgery, Centre Hospitalier Universitaire Sainte-Justine, Montréal, Québec, Canada.

出版信息

EJVES Vasc Forum. 2021 Jun 21;52:41-48. doi: 10.1016/j.ejvsvf.2021.06.007. eCollection 2021.

Abstract

INTRODUCTION

Congenital aneurysms of major arteries are very rare diagnoses and prognosis can be poor if treatment is not initiated rapidly. This is the presentation of two cases of infants with congenital iliac aneurysms who underwent treatment in the neonatal period. The report then proceeds with a literature review of paediatric iliac aneurysms.

REPORT

A female neonate was diagnosed antenatally with right common iliac (CIA) and internal iliac (IIA) artery aneurysms. Embolisation on day of life (DOL) eight was impossible because of partial thrombosis. The infant was subsequently observed for several months and the aneurysm was injected percutaneously with thrombin on DOL 78. A small residual aneurysm was coil embolised at five months of age. Satisfactory results were observed at one year follow up. A female neonate was diagnosed antenatally on routine third trimester ultrasound with voluminous, bilateral CIA aneurysms. The patient underwent surgery on DOL 9 for aneurysm resection and microsurgical vascular reconstruction. The intervention was successful with triphasic flow through the anastomoses on colour Doppler ultrasound at six week follow up.

DISCUSSION

Ten cases of congenital iliac aneurysms have been reported previously, with just two diagnosed in the neonatal period and eight undergoing surgical intervention. Definitive management to avoid aneurysm rupture or thrombosis should be timed carefully, and sometimes delayed with watchful waiting, to maximise success and minimise complications. Surgery is the key treatment modality, but endovascular intervention can be considered in selected cases. Congenital iliac aneurysms should be addressed at the safest time for the patient. Following resection, primary microvascular anastomosis is the ideal reconstructive technique, but other options for neonates have been described. Endovascular treatment should be considered for anatomically amenable saccular aneurysms.

摘要

引言

主要动脉的先天性动脉瘤诊断极为罕见,若不迅速开始治疗,预后可能很差。本文介绍了两例先天性髂动脉瘤婴儿在新生儿期接受治疗的情况。报告随后对小儿髂动脉瘤进行了文献综述。

病例报告

一名女新生儿在产前被诊断出右髂总动脉(CIA)和髂内动脉(IIA)动脉瘤。由于部分血栓形成,出生后第8天无法进行栓塞治疗。随后对该婴儿进行了数月观察,并在出生后第78天经皮注射凝血酶治疗动脉瘤。5个月大时对小的残余动脉瘤进行了弹簧圈栓塞。1年随访时观察到满意的结果。一名女新生儿在孕晚期常规超声检查中被产前诊断为双侧巨大CIA动脉瘤。该患者在出生后第9天接受了动脉瘤切除和显微外科血管重建手术。6周随访时彩色多普勒超声显示吻合口有三相血流,手术成功。

讨论

此前已报告10例先天性髂动脉瘤病例,仅2例在新生儿期被诊断,8例接受了手术干预。为避免动脉瘤破裂或血栓形成,明确的治疗应仔细安排时间,有时需谨慎等待并延迟治疗,以实现最大成功率并减少并发症。手术是关键的治疗方式,但在特定情况下可考虑血管内介入治疗。应在对患者最安全的时间处理先天性髂动脉瘤。切除后,原发性微血管吻合是理想的重建技术,但也描述了适用于新生儿的其他选择。对于解剖结构适合的囊状动脉瘤,应考虑血管内治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/abda/8424503/002e8883a747/gr1.jpg

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