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一种 8-芳基硒 BODIPY 荧光探针,用于快速灵敏地鉴别活细胞中的生物硫醇。

An 8-arylselenium BODIPY fluorescent probe for rapid and sensitive discrimination of biothiols in living cells.

机构信息

Department of Chemistry, University of Science and Technology of China, Hefei 230026, P. R. China.

Department of Polymer Science and Engineer, University of Science and Technology of China, Hefei 230026, P. R. China.

出版信息

Chem Commun (Camb). 2021 Oct 5;57(79):10198-10201. doi: 10.1039/d1cc03912a.

Abstract

By introducing 8-arylselenium as the active group, a BODIPY fluorescent probe ASeBD was constructed for rapid and sensitive detection and dual-channel discrimination of GSH and Cys/Hcy in solution and in living cells, and its mechanism was demonstrated.

摘要

通过引入 8-芳基硒作为活性基团,构建了一种 BODIPY 荧光探针 ASeBD,用于快速灵敏地检测和双通道区分溶液和活细胞中的 GSH 和 Cys/Hcy,并证明了其机制。

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