Donna A, Betta P G, Robutti F, Bellingeri D
Department of Pathology, City Hospital, U.S.S.L., Alessandria, Italy.
G Ital Med Lav. 1986 May-Jul;8(3-4):119-21.
A statistically significant increase (p less than 0.001) of lymphomas (4 of plasmacell type and two of histiocytic type) was found in a group of 30 Swiss albino mice which were given intraperitoneally 0.25 cc of a 2 ppm solution of atrazine for 13 times every third day to total administration of 0.26 mg of Atrazine/kg of body weight. Lymphomas arising in two groups of 50 controls was 0 and 1 respectively.
在一组30只瑞士白化小鼠中,每三天腹腔注射0.25毫升2 ppm的阿特拉津溶液,共注射13次,使每千克体重的阿特拉津总给药量达到0.26毫克。结果发现淋巴瘤的发生率有统计学显著增加(p小于0.001),其中浆细胞型淋巴瘤4例,组织细胞型淋巴瘤2例。两组各50只对照小鼠中出现的淋巴瘤分别为0例和1例。