Department of Medical Oncology, Alexis Multispeciality Hospital, Nagpur, Maharashtra, India.
Department of Radiology, Alexis Multispeciality Hospital, Nagpur, Maharashtra, India.
Pan Afr Med J. 2021 Jun 28;39:150. doi: 10.11604/pamj.2021.39.150.28903. eCollection 2021.
Blastoid variant of mantle cell lymphoma (MCL) is an aggressive and incurable form of B-cell lymphoma. Various chemo-immunotherapy regimens have been used with a limited success. Autologous stem cell transplant (ASCT) is being increasingly recommended in first remission for patients with blastoid variant MCL. Here, we describe the case of a 45-year-old lady suffering from blastoid variant of MCL. Patient was administered R-CHOP and underwent autologous stem cell transplant (ASCT). Currently, patient is disease-free and is on a regular follow up for 26 months now. This is an extremely rare case documented in the Indian literature with a long survival post-transplant.
母细胞性淋巴瘤（MCL）的 blastoid 变体是一种侵袭性且无法治愈的 B 细胞淋巴瘤。已经使用了各种化疗免疫疗法，但收效有限。自体干细胞移植（ASCT）越来越多地被推荐用于 blastoid 变体 MCL 的首次缓解期患者。在这里，我们描述了一位 45 岁女性患有 blastoid 变体 MCL 的病例。患者接受了 R-CHOP 治疗，并进行了自体干细胞移植（ASCT）。目前，患者无疾病且在移植后 26 个月定期随访。这是印度文献中记录的一个极其罕见的病例，移植后生存时间较长。
