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侵犯臂丛神经的Castleman病的罕见表现。

Unusual Presentation of Castleman's Disease Encroaching on the Brachial Plexus.

作者信息

Shah Rahil H, Cioffi-Lavina Maureen, Jaguan Abraham, Varella Marcia

机构信息

Internal Medicine, Jackson Memorial Hospital/University of Miami, Miami, USA.

Department of Pathology, Mercy Hospital, Miami, USA.

出版信息

Cureus. 2021 Aug 7;13(8):e16981. doi: 10.7759/cureus.16981. eCollection 2021 Aug.

DOI:10.7759/cureus.16981
PMID:34527461
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8421014/
Abstract

Castleman's disease is an uncommon benign lymphoproliferative disorder that commonly involves the mediastinum. We report an unusual case that involves the presentation of unicentric Castleman's disease in a 52-year-old female. The patient had a supraclavicular mass extending onto the brachial plexus. The approach to the treatment and plan for supraclavicular masses is complex due in part to the extensive list of differential diagnoses possible. In this case specifically, while the mass was ultimately determined to be benign, post-surgery, the location of the mass intraoperatively made for a very technically challenging and complex dissection. Post surgical resection, the patient reported no complications. This case highlights the importance of clinical judgement, imaging and surgical technique in removing a mass encroaching on the brachial plexus.

摘要

卡斯尔曼病是一种罕见的良性淋巴增生性疾病,常累及纵隔。我们报告一例不寻常的病例,为一名52岁女性出现单中心卡斯尔曼病。患者有一个延伸至臂丛神经的锁骨上肿块。锁骨上肿块的治疗方法和计划很复杂,部分原因是可能的鉴别诊断范围广泛。在这个具体病例中,虽然肿块最终被确定为良性,但术后发现肿块在术中的位置使得解剖操作极具技术挑战性且复杂。手术切除后,患者未报告有并发症。该病例突出了临床判断、影像学检查和手术技术在切除侵犯臂丛神经的肿块中的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32d0/8421014/9e67e6e1ca14/cureus-0013-00000016981-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32d0/8421014/39e6bed2b150/cureus-0013-00000016981-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32d0/8421014/c499c1a32fca/cureus-0013-00000016981-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32d0/8421014/e9df26218728/cureus-0013-00000016981-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32d0/8421014/9e67e6e1ca14/cureus-0013-00000016981-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32d0/8421014/39e6bed2b150/cureus-0013-00000016981-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32d0/8421014/c499c1a32fca/cureus-0013-00000016981-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32d0/8421014/e9df26218728/cureus-0013-00000016981-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32d0/8421014/9e67e6e1ca14/cureus-0013-00000016981-i04.jpg

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本文引用的文献

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[Analysis of the diagnosis and treatment of Castleman disease originating in the head and neck].[头颈部Castleman病的诊断与治疗分析]
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2018 Jun 5;32(11):860-864. doi: 10.13201/j.issn.1001-1781.2018.11.015.
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Castleman's Disease: a Suprarenal Surprise!卡斯特尔曼病:肾上腺的意外发现!
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3
Rare Forms of Castleman Disease Mimicking Malignancy: Mesenteric and Pancreatic Involvement.
酷似恶性肿瘤的Castleman病罕见类型:肠系膜及胰腺受累
Cureus. 2018 Mar 12;10(3):e2310. doi: 10.7759/cureus.2310.
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[Unicentric Castleman's disease in cervical back space neck].颈部后间隙的单中心Castleman病
Rev Med Inst Mex Seguro Soc. 2017 Sep-Oct;55(5):660-665.
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Epidemiology of Castleman Disease.卡斯特曼病的流行病学
Hematol Oncol Clin North Am. 2018 Feb;32(1):1-10. doi: 10.1016/j.hoc.2017.09.001.
6
Clinical and pathological characteristics of HIV- and HHV-8-negative Castleman disease.HIV和HHV-8阴性的Castleman病的临床和病理特征
Blood. 2017 Mar 23;129(12):1658-1668. doi: 10.1182/blood-2016-11-748855. Epub 2017 Jan 18.
7
Clinical spectrum and survival analysis of 145 cases of HIV-negative Castleman's disease: renal function is an important prognostic factor.145 例 HIV 阴性血管滤泡性淋巴结增生症患者的临床特征及生存分析:肾功能是一个重要的预后因素。
Sci Rep. 2016 Mar 31;6:23831. doi: 10.1038/srep23831.
8
Parsonage-Turner syndrome during the treatment of HIV/HHV8-related multicentric Castleman disease.人类免疫缺陷病毒/人类疱疹病毒8相关多中心Castleman病治疗期间的Parsonage-Turner综合征
Rev Clin Esp (Barc). 2014 Mar;214(2):e15-7. doi: 10.1016/j.rce.2013.11.009. Epub 2013 Dec 21.
9
The clinical spectrum of Castleman's disease.卡斯特曼病的临床谱。
Am J Hematol. 2012 Nov;87(11):997-1002. doi: 10.1002/ajh.23291. Epub 2012 Jul 13.
10
Castleman disease: an update on classification and the spectrum of associated lesions.卡斯特曼病:分类及相关病变谱的最新进展
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