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用于测试局部止汗活性的湿摄技术

Hygrophotographic technique for testing local antiperspirant activity.

作者信息

Sivadjian J

出版信息

Pharmacology. 1978;16(4):214-6. doi: 10.1159/000136769.

DOI:10.1159/000136769
PMID:345290
Abstract

Bilateral stopping of plantar perspiration in the mouse was obtained by application of a cotton-wool swab soaked in a 3% solution of BRL 556 in 60% ethanol for 1--2 min to the plantar surface of its right hind paw. For humans, aerosols which are at present on the market produce a sensible reduction in palmar sweating. The effect was recorded and illustrated by a modified hygrophotographic technique in which the sweat, released in the form of water vapor, was recorded by the hygrophotographic film, without any contact with the skin. In the mouse, the recording was carried out by the application to the plantar surface of a piece of hygrophotographic film, by the aid of an adhesive tape.

摘要

通过将浸有3%BRL 556于60%乙醇中的棉拭子敷于小鼠右后爪足底表面1至2分钟,可实现小鼠双侧足底排汗停止。对于人类而言,目前市面上的气雾剂可显著减少手掌出汗。采用改良的湿度摄影技术记录并展示了该效果,在该技术中,以水蒸气形式释放的汗液由湿度摄影胶片记录,且不与皮肤有任何接触。在小鼠中,通过借助胶带将一块湿度摄影胶片敷于足底表面来进行记录。

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