[输血过敏反应]

[Allergic reactions to transfusion].

作者信息

Hergon E, Paitre M L, Coeffic B, Piard N, Bidet J M

出版信息

Allerg Immunol (Paris). 1987 Apr;19(4):128-34.

Abstract

Frequent allergic reactions following transfusion are observed. Usually, they are benign but sometimes we observe severe allergic reactions. Adverse reactions may be brought about by least two mechanisms. First, immediate-type hypersensibility reactions due to IgE. Secondly, anaphylactic-type reactions due to interaction between transfused IgA and class specific anti IgA in the recipient's plasma. They are characterized by their severest form (anaphylactic shock). The frequency of severe reactions following the transfusion blood plasma is very low. These transfusion reactions are complement-mediated and kinins-mediated. Prevention of allergic reactions is necessary among blood donors and recipients.

摘要

输血后常观察到频繁的过敏反应。通常，它们是良性的，但有时我们会观察到严重的过敏反应。不良反应可能由至少两种机制引起。第一，由于IgE导致的速发型超敏反应。第二，由于输入的IgA与受者血浆中的类特异性抗IgA之间的相互作用导致的过敏样反应。它们的特征是最严重的形式（过敏性休克）。输血血浆后严重反应的发生率非常低。这些输血反应是由补体介导和激肽介导的。在献血者和受者中预防过敏反应是必要的。