Salastekar Ninad, Saunders Alexis, Patel Kushal, Willer Katherine
Department of Radiology, SUNY Upstate Medical University, 750 East Adam Street, Syracuse, NY 13210, USA.
Radiol Res Pract. 2021 Sep 6;2021:9634938. doi: 10.1155/2021/9634938. eCollection 2021.
To evaluate the association between preprocedural hypertension and the risk of prolonged bleeding following image-guided core needle breast biopsy in nonpregnant/nonlactating women.
A single institution-based, retrospective cohort study of 400 women who underwent image-guided core needle breast biopsy was conducted. Males and pregnant and lactating women were excluded. Preprocedural systolic or diastolic blood pressure greater than 140 or 90 mm of Hg, respectively, was defined as hypertension. Prolonged bleeding was defined >15 minutes of local, manual pressure required to achieve hemostasis following the biopsy. Severe bleeding complications defined as clinical significant hematoma formation, prolonged bleeding requiring an ER visit, hospitalization, or surgical intervention were also recorded.
The difference in the mean time for which manual pressure was held after biopsy for patients with and without preprocedural hypertension was not statistically significant (13 ± 7 vs. 13 ± 8 minutes, respectively, = 0.856). There was no difference in the number of patients requiring manual postoperative pressure >15 minutes between those with preprocedural hypertension and the normotensive patients (13% vs. 12%, respectively, = 0.765). Bivariate analysis demonstrated statistically significant association between prolonged bleeding and current antithrombotic or antiplatelet medication use ( = 0.010), the use of stereotactic guidance ( = 0.019), and a tethered vacuum-assisted device ( = 0.045). The use of a tethered vacuum-assisted biopsy device was the only variable associated with prolonged bleeding in the multivariate model ( = 0.044).
Preprocedural hypertension is not a risk factor for prolonged bleeding following image-guided core needle breast biopsies in nonpregnant/nonlactating women.
评估非妊娠/非哺乳期女性在影像引导下经皮乳腺穿刺活检术前高血压与出血时间延长风险之间的关联。
对400例行影像引导下经皮乳腺穿刺活检的女性进行了一项基于单机构的回顾性队列研究。排除男性以及妊娠和哺乳期女性。术前收缩压或舒张压分别大于140或90 mmHg定义为高血压。出血时间延长定义为活检后需要局部手动按压止血>15分钟。还记录了严重出血并发症,定义为临床上有意义的血肿形成、需要急诊就诊、住院或手术干预的出血时间延长。
术前有高血压和无高血压患者活检后手动按压的平均时间差异无统计学意义(分别为13±7分钟和13±8分钟,P = 0.856)。术前高血压患者和血压正常患者中术后需要手动按压>15分钟的患者数量无差异(分别为13%和12%,P = 0.765)。二元分析显示出血时间延长与当前使用抗血栓或抗血小板药物(P = 0.010)、使用立体定向引导(P = 0.019)和使用栓系真空辅助装置(P = 0.045)之间存在统计学显著关联。在多变量模型中,使用栓系真空辅助活检装置是与出血时间延长相关的唯一变量(P = 0.044)。
在非妊娠/非哺乳期女性的影像引导下经皮乳腺穿刺活检中,术前高血压不是出血时间延长的危险因素。