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儿童患者急性 COVID-19 感染相关的坏死性播散性急性脑白质病和脑微出血

Acute COVID-19 Infection Associated With Necrotizing Disseminated Acute Leukoencephalopathy and Brain Microhemorrhages in a Pediatric Patient.

机构信息

From the East Carolina University, Vidant Medical Center, Brody School of Medicine, Greenville, NC.

出版信息

Pediatr Infect Dis J. 2021 Dec 1;40(12):e493-e496. doi: 10.1097/INF.0000000000003302.

DOI:10.1097/INF.0000000000003302
PMID:34533490
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8575091/
Abstract

We present a case of a 14-year-old, previously healthy female, admitted with acute coronavirus disease 2019 infection and new-onset seizures secondary to virus-associated necrotizing disseminated acute leukoencephalopathy. Her symptoms resolved completely with intravenous immunoglobulin and steroids. Pathophysiology and prognosis of neurologic manifestations of coronavirus disease 2019 remain unclear.

摘要

我们报告了一例 14 岁、既往健康的女性患者，因急性 2019 年冠状病毒病感染和病毒相关性坏死性播散性急性脑白质病继发的新发癫痫入院。她的症状在静脉注射免疫球蛋白和类固醇治疗后完全缓解。2019 年冠状病毒病的神经系统表现的发病机制和预后尚不清楚。

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引用本文的文献

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Acute necrotizing encephalopathy in children with COVID-19: a retrospective study of 12 cases.新型冠状病毒肺炎患儿的急性坏死性脑病：12例回顾性研究
Front Neurol. 2023 Aug 2;14:1184864. doi: 10.3389/fneur.2023.1184864. eCollection 2023.
2
Neurological Manifestations of Coronavirus Disease 2019 and Mpox in Pediatric Patients and Their Management: A State-of-the-Art Systematic Review.新型冠状病毒病 2019 与猴痘在儿科患者中的神经表现及其治疗：最新系统评价。
Pediatr Neurol. 2023 Sep;146:65-78. doi: 10.1016/j.pediatrneurol.2023.05.011. Epub 2023 May 19.