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利用潜在类别和量子模型评估医疗保健中的公平性:两个故事。

Using latent class and quantum models to value equity in health care: a tale of 2 stories.

机构信息

Department of Health Outcomes Research & Policy, Harrison School of Pharmacy, Auburn University, Auburn, AL.

出版信息

J Manag Care Spec Pharm. 2021 Sep;27(9-a Suppl):S14-S18. doi: 10.18553/jmcp.2021.27.9-a.s14.

Abstract

Cost-effectiveness analysis (CEA) with quality-adjusted life-year (QALY) was introduced to address health equity concerns in value assessment. However, QALY fails to capture patient preference. Stated preference methods (eg, discrete choice experiment [DCE]) have been increasingly used to incorporate patient preference into the value assessment framework in health care. Still, ones with a moral dimension such as health equity do not exist. The objective of this paper was to describe 2 stated preference approaches that can empirically value health equity. First, the decision-maker perceptions of the prevalence of equity dimensions in DCE choice tasks are identified. A latent class model based on random utility theory is proposed to derive the value of equity from the decision makers with different perceptions of the prevalence of equity dimensions. Second, equity attributes are incorporated in DCE choice tasks, and a quantum choice model, which can capture stochasticity during the decision process in the mind of the decision makers, is used to value the equity. These approaches will improve existing value assessment methods to address health equity adequately. This study received no outside funding. Ngorsuraches has received research grants from Bristol Myers Squibb and through the University of Utah and PhRMA Foundation.

摘要

成本效益分析(CEA)与质量调整生命年(QALY)的结合,旨在解决价值评估中的公平性问题。然而,QALY 无法捕捉患者的偏好。基于偏好的方法(例如,离散选择实验[DCE])已被越来越多地用于将患者偏好纳入医疗保健的价值评估框架中。然而,像健康公平这样具有道德维度的偏好还不存在。本文的目的是描述两种可用于实证评估健康公平的基于偏好的方法。首先,确定决策者在 DCE 选择任务中对公平维度的出现的感知。基于随机效用理论的潜在类别模型被提出,用于从对公平维度出现的感知不同的决策者中得出公平的价值。其次,在 DCE 选择任务中纳入公平属性,并使用量子选择模型,该模型可以捕捉决策者思维中的决策过程中的随机性,来评估公平的价值。这些方法将改进现有的价值评估方法,以充分解决健康公平问题。本研究没有外部资金支持。Ngorsuraches 从 Bristol Myers Squibb 获得了研究资助,并通过犹他大学和 PhRMA 基金会获得了资助。

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