Matsunaga H
Department of Neuropsychiatry, Kurume University School of Medicine.
Jpn J Psychiatry Neurol. 1987 Dec;41(4):637-44. doi: 10.1111/j.1440-1819.1987.tb00420.x.
Although idiopathic CNS hypersomnolence is the third most frequent hypersomnia diagnosis, the syndrome is still unfamiliar to physicians, especially in Japan. In the Sleep Disorders Clinic of Kurume University Hospital, seven patients were diagnosed as idiopathic CNS hypersomnolence. All the patients complained of persistent daytime sleepiness, difficulty in morning awakening and lengthening of nocturnal sleep. Their daytime sleepiness had not been reduced even when they have taken sufficient nocturnal sleep. Various autonomic symptoms were observed, but what has noticeably been absent were cataplexy, sleep paralysis, sleep attack, sleep apnea or any other identifiable neurological disorders. The onset of the syndrome in four of the seven patients occurred in their teens. No therapeutic effects had been found after undergoing medical treatments.
尽管特发性中枢神经系统过度嗜睡是第三常见的过度嗜睡诊断，但该综合征对医生来说仍不熟悉，尤其是在日本。在久留米大学医院睡眠障碍诊所，有7名患者被诊断为特发性中枢神经系统过度嗜睡。所有患者均主诉持续性日间嗜睡、早晨觉醒困难和夜间睡眠时间延长。即使他们夜间睡眠充足，日间嗜睡也未减轻。观察到各种自主神经症状，但明显没有猝倒、睡眠麻痹、睡眠发作、睡眠呼吸暂停或任何其他可识别的神经系统疾病。7名患者中有4名在青少年时期发病。接受治疗后未发现治疗效果。
