Departments of Surgery.
The Ruth and Bruce Rappaport Faculty of Medicine, Technion, Israel Institute of Technology, Haifa.
Surg Laparosc Endosc Percutan Tech. 2021 Sep 17;32(1):73-78. doi: 10.1097/SLE.0000000000001005.
The aim was to compare the short-term and long-term outcomes of patients with metastatic colorectal cancer (CRC) undergoing laparoscopic versus open colorectal resection with simultaneous resection for liver metastases. Currently there is a lack of studies that have investigated the oncosurgical aspects and the short and long-term outcomes from these procedures.
A retrospective study of patients who underwent simultaneous resections for CRC and synchronous liver metastases between 2008 and 2019 in 2 university affiliated medical centers.
Sixty-three patients were identified of whom 21 had successful laparoscopic simultaneous resections. In 43% of patients, the primary tumor was located in the right colon. The 3-year overall survival and disease-free survival rates were 87% and 48%, respectively. When compared with a separate control group of 42 patients who underwent conventional open resections, the laparoscopic approach was associated with an increased operative time (286 vs. 225 min, P=0.05), but a shorter hospital stay (6 vs. 8 d, P=0.008).
Simultaneous laparoscopic colorectal and parenchymal sparing liver resection for metastatic CRC is safe, feasible, and it is a preferable approach because of better short-term outcome compared with open surgery while not compromising survival and disease recurrence.
本研究旨在比较腹腔镜与开腹结直肠切除术联合同期肝转移灶切除术治疗转移性结直肠癌（CRC）患者的短期和长期疗效。目前，缺乏研究调查这些手术的肿瘤外科方面以及其短期和长期疗效。
本研究为回顾性研究，纳入了 2008 年至 2019 年在 2 所大学附属医院行 CRC 和同步肝转移灶切除术的患者。
共纳入 63 例患者，其中 21 例成功实施了腹腔镜同期切除术。43%的患者原发肿瘤位于右半结肠。患者的 3 年总生存率和无病生存率分别为 87%和 48%。与接受传统开腹切除术的 42 例对照患者相比，腹腔镜组的手术时间更长（286 分钟比 225 分钟，P=0.05），但住院时间更短（6 天比 8 天，P=0.008）。
对于转移性 CRC，同期腹腔镜结直肠和实质保留肝切除术是安全可行的，与开腹手术相比，具有更好的短期疗效，而不会影响生存和疾病复发。
