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冷冻消融治疗不典型房室结折返性心动过速。

Cryoablation of atypical atrioventricular nodal reentry tachycardia.

机构信息

Department of Cardiology, Karolinska University Hospital, Stockholm, Sweden.

Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden.

出版信息

J Cardiovasc Electrophysiol. 2021 Nov;32(11):2971-2978. doi: 10.1111/jce.15244. Epub 2021 Sep 22.

Abstract

AIM

Data on ablation for atypical recurrent atrioventricular nodal reentry tachycardia (AVNRT) and long-term follow-up are generally sparse. Furthermore, the rate of recurrence and safety of cryoablation for atypical AVNRT has not been established. We compared patients cryoablated for atypical AVNRT and typical AVNRT during long-term follow-up.

METHODS

All patients (n = 2612) who underwent catheter ablation for AVNRT at the Karolinska University Hospital between January 2009 and August 2019 were analyzed. A total of 91 patients undergoing first-time cryoablation for atypical AVNRT were included. A control group with first-time cryoablation for typical AVNRT was matched in a 1:1 ratio. Patients were followed-up for recurrences for a median of 5.0 years (interquartile range: 3.1-7.5 years).

RESULTS

After 5 years, AVNRT recurrence occurred in 10 patients (11.0%) in the atypical AVNRT group and in 8 patients (8.8%) in the typical AVNRT group (hazard ratio: 1.31 [95% confidence interval: 0.52-3.32]; p = 0.568). The duration of the index procedure was significantly longer for atypical compared to typical AVNRT ablation (132.1 ± 49.2 min vs. 110.1 ± 38.8 min; p = 0.001). Transient AV blocks occurred in a similar fashion in the atypical compared to typical group (11 [12.1%] vs. 4 [4.9%]; p = 0.103). However, no ablation induced persistent AV block developed in either group.

CONCLUSION

Cryoablation for atypical AVNRT showed similar rate of recurrences and safety compared to typical AVNRT during long-term follow-up.

摘要

目的

关于非典型房室结折返性心动过速(AVNRT)消融和长期随访的数据通常很少。此外,冷冻消融治疗非典型 AVNRT 的复发率和安全性尚未确定。我们比较了长期随访中接受冷冻消融治疗非典型 AVNRT 和典型 AVNRT 的患者。

方法

分析了 2009 年 1 月至 2019 年 8 月期间在卡罗林斯卡大学医院接受 AVNRT 导管消融的所有患者(n=2612)。共纳入 91 例首次接受冷冻消融治疗非典型 AVNRT 的患者。以 1:1 的比例匹配首次接受冷冻消融治疗典型 AVNRT 的对照组。患者的中位随访时间为 5.0 年(四分位距:3.1-7.5 年)。

结果

5 年后,非典型 AVNRT 组有 10 例(11.0%)患者出现 AVNRT 复发,典型 AVNRT 组有 8 例(8.8%)患者复发(风险比:1.31 [95%置信区间:0.52-3.32];p=0.568)。与典型 AVNRT 消融相比,非典型 AVNRT 消融的手术时间明显较长(132.1±49.2 分钟 vs. 110.1±38.8 分钟;p=0.001)。非典型组与典型组发生一过性房室阻滞的方式相似(11 例[12.1%] vs. 4 例[4.9%];p=0.103)。然而,两组均未出现消融诱导的持续性房室阻滞。

结论

长期随访中,冷冻消融治疗非典型 AVNRT 的复发率和安全性与典型 AVNRT 相似。

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