• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Relieving job: Dupilumab in autosomal dominant STAT3 hyper-IgE syndrome.

作者信息

Staudacher Olga, Krüger Renate, Kölsch Uwe, Thee Stephanie, Gratopp Alexander, Wahn Volker, Lau Susanne, von Bernuth Horst

机构信息

Department of Pediatric Respiratory Medicine, Immunology, and Critical Care Medicine, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany; Labor Berlin-Charité Vivantes GmbH, Department of Immunology, Berlin, Germany.

Department of Pediatric Respiratory Medicine, Immunology, and Critical Care Medicine, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.

出版信息

J Allergy Clin Immunol Pract. 2022 Jan;10(1):349-351.e1. doi: 10.1016/j.jaip.2021.08.042. Epub 2021 Sep 16.

DOI:10.1016/j.jaip.2021.08.042
PMID:34536614
Abstract
摘要

相似文献

1
Relieving job: Dupilumab in autosomal dominant STAT3 hyper-IgE syndrome.缓解性工作：度普利尤单抗治疗常染色体显性 STAT3 高 IgE 综合征
J Allergy Clin Immunol Pract. 2022 Jan;10(1):349-351.e1. doi: 10.1016/j.jaip.2021.08.042. Epub 2021 Sep 16.
2
Remission of eczema and recovery of Th1 polarization following treatment with Dupilumab in STAT3 hyper IgE syndrome.在STAT3高IgE综合征中使用度普利尤单抗治疗后湿疹缓解及Th1极化恢复。
Pediatr Allergy Immunol. 2022 Apr;33(4):e13770. doi: 10.1111/pai.13770.
3
Dupilumab to treat severe atopic dermatitis in autosomal dominant hyper-IgE syndrome.度普利尤单抗治疗常染色体显性高免疫球蛋白E综合征中的重度特应性皮炎。
Clin Immunol. 2020 Jun;215:108452. doi: 10.1016/j.clim.2020.108452. Epub 2020 Apr 29.
4
Dupilumab treatment of eczema in a child with STAT3 hyper-immunoglobulin E syndrome.度普利尤单抗治疗一名患有STAT3高免疫球蛋白E综合征儿童的湿疹
J Eur Acad Dermatol Venereol. 2022 May;36(5):e367-e369. doi: 10.1111/jdv.17889. Epub 2022 Jan 8.
5
[STAT3 mutation in a child with hyper-IgE syndrome and incomplete clinical features].[一名具有不完全临床特征的高IgE综合征患儿的STAT3突变]
Przegl Lek. 2015;72(12):787-90.
6
Diffuse large B cell lymphoma in hyper-IgE syndrome due to STAT3 mutation.由 STAT3 突变引起的高免疫球蛋白 E 综合征中的弥漫性大 B 细胞淋巴瘤。
J Clin Immunol. 2010 Nov;30(6):886-93. doi: 10.1007/s10875-010-9452-z. Epub 2010 Sep 22.
7
Omalizumab in the Treatment of Hyper-IgE Syndrome: 2 Case Reports.奥马珠单抗治疗高免疫球蛋白E综合征：2例报告
J Investig Allergol Clin Immunol. 2020;30(3):191-192. doi: 10.18176/jiaci.0469. Epub 2019 Dec 10.
8
Hyper-IgE syndrome with a novel mutation of the STAT3 gene.伴有信号转导子和转录激活子3（STAT3）基因新突变的高免疫球蛋白E综合征
Clin Exp Dermatol. 2016 Aug;41(6):687-9. doi: 10.1111/ced.12865. Epub 2016 Jun 23.
9
Rapid Transition of Facial Features from Early to Mid - Adolescence in Autosomal Dominant Hyper IgE Syndrome with a STAT3 Variation.伴有STAT3变异的常染色体显性高IgE综合征患者面部特征从青春期早期到中期的快速转变
Indian J Pediatr. 2018 Jul;85(7):595-596. doi: 10.1007/s12098-017-2603-y. Epub 2018 Jan 24.
10
Autosomal Dominant Hyper-IgE Syndrome Without Significantly Elevated IgE.无显著升高的IgE的常染色体显性高IgE综合征。
J Clin Immunol. 2019 Nov;39(8):827-831. doi: 10.1007/s10875-019-00683-8. Epub 2019 Aug 29.

引用本文的文献

1
β-Actin Deficiency in Baraitser-Winter Syndrome Type 1 Disrupts T-Cell Function and Immune Regulation: Implications for Targeted Therapy in Actinopathies.1型巴赖特-温特综合征中的β-肌动蛋白缺乏会破坏T细胞功能和免疫调节：对肌动蛋白病靶向治疗的启示。
J Clin Immunol. 2025 Aug 1;45(1):120. doi: 10.1007/s10875-025-01906-x.
2
Pathological IgE Production in Inborn Errors of Immunity and Beyond.免疫先天性疾病及其他情况下的病理性IgE产生
Immunol Rev. 2025 Jul;332(1):e70053. doi: 10.1111/imr.70053.
3
Hyper IgE Syndromes: Understanding, Management, and Future Perspectives: A Narrative Review.
高免疫球蛋白E综合征：理解、管理与未来展望：一篇叙述性综述
Health Sci Rep. 2025 Mar 19;8(3):e70497. doi: 10.1002/hsr2.70497. eCollection 2025 Mar.
4
The genetics of hyper IgE syndromes.高免疫球蛋白E综合征的遗传学
Front Immunol. 2025 Feb 18;16:1516068. doi: 10.3389/fimmu.2025.1516068. eCollection 2025.
5
Inborn errors of immunity with atopic phenotypes in the allergy and immunology clinic: a practical review.过敏与免疫门诊中具有特应性表型的先天性免疫缺陷：实用综述
Curr Opin Allergy Clin Immunol. 2025 Apr 1;25(2):105-114. doi: 10.1097/ACI.0000000000001059. Epub 2025 Feb 13.
6
Improvement in Atopic Dermatitis and Recurrent Infection With Dupilumab in Children With Distinct Genetic Types of Hyper-IgE Syndrome: A Case Series and Literature Review.度普利尤单抗治疗不同遗传类型高IgE综合征儿童特应性皮炎及反复感染的疗效：病例系列及文献综述
Pediatr Dermatol. 2025 Mar-Apr;42(2):376-382. doi: 10.1111/pde.15780. Epub 2024 Oct 18.
7
Monogenic Inborn Errors of Immunity with impaired IgG response to polysaccharide antigens but normal IgG levels and normal IgG response to protein antigens.对多糖抗原的IgG反应受损但IgG水平正常且对蛋白质抗原的IgG反应正常的单基因遗传性免疫缺陷病。
Front Pediatr. 2024 Jun 12;12:1386959. doi: 10.3389/fped.2024.1386959. eCollection 2024.
8
Hyper-IgE syndrome: a case report.高免疫球蛋白E综合征：一例报告。
Ann Med Surg (Lond). 2024 Jan 3;86(2):1205-1209. doi: 10.1097/MS9.0000000000001670. eCollection 2024 Feb.
9
Hyper IgE syndrome-related disease treated with dupilumab: A case report.度普利尤单抗治疗高IgE综合征相关疾病：一例报告
Clin Case Rep. 2023 Sep 13;11(9):e7614. doi: 10.1002/ccr3.7614. eCollection 2023 Sep.
10
Early intervention in STAT3 dominant negative disease.对信号转导和转录激活因子3（STAT3）显性负性疾病的早期干预。
J Allergy Clin Immunol Pract. 2023 Dec;11(12):3795-3798.e1. doi: 10.1016/j.jaip.2023.08.044. Epub 2023 Sep 6.